SIAN: software for structural identifiability analysis of ODE models
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Updated: Jan 31, 2026
Three-Dimensional Shape Modeling and Analysis of Brain Structures
Published on: November 14, 2019
Hoon Hong1, Alexey Ovchinnikov2, Gleb Pogudin3
1Department of Mathematics, North Carolina State University, Raleigh, NC, USA.
Summary:
Biological processes are often modeled by ordinary differential equations with unknown parameters. The unknown parameters are usually estimated from experimental data. In some cases, due to the structure of the model, this estimation problem does not have a unique solution even in the case of continuous noise-free data. It is therefore desirable to check the uniqueness a priori before carrying out actual experiments. We present a new software SIAN (Structural Identifiability ANalyser) that does this. Our software can tackle problems that could not be tackled by previously developed packages.
Availability And Implementation:
SIAN is open-source software written in Maple and is available at https://github.com/pogudingleb/SIAN.
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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