Glutathione modified Ag nanoparticles as efficient detector for pyrimethanil

Area of Science:

• Nanotechnology
• Analytical Chemistry
• Environmental Science

Background:

• Pesticide detection is crucial for environmental and food safety.
• Development of selective and sensitive chemosensors is an ongoing challenge.
• Silver nanoparticles (Ag NPs) offer unique optical properties for sensing applications.

Purpose of the Study:

• To develop a glutathione-modified silver nanoparticle (GSH-Ag NP) based chemosensor.
• To detect the pesticide pyrimethanil in aqueous solutions.
• To achieve selective, sensitive, and colorimetric detection of pyrimethanil.

Main Methods:

• Synthesis of GSH-Ag NPs via reduction of AgNO3 with NaBH4 and modification with glutathione.
• Utilizing localized surface plasmon resonance (LSPR) properties of Ag NPs.
• Employing colorimetric assays for visible signal transduction.
• Characterization using 1H NMR, FT-IR, and computational simulation for selectivity confirmation.

Main Results:

• GSH-Ag NPs exhibited high selectivity for pyrimethanil over other pesticides.
• Selective recognition was translated into a visible color change.
• Quantitative detection showed a linear relationship from 10 μM to 1 mM.
• A low detection limit of 3.87 μM was achieved for pyrimethanil.

Conclusions:

• GSH-Ag NPs serve as an effective colorimetric chemosensor for pyrimethanil detection.
• The sensor offers a practical method for analyzing pyrimethanil in real-world samples.
• This approach provides a sensitive and selective tool for pesticide monitoring.