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Updated: Jan 31, 2026

Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Two new phenolic glycosides from the seeds of Citrullus lanatus
Xiao-Qian Zhang1, Jing Shi1, Shi-Xiu Feng2
1Key Laboratory of Xinjiang Phytomedicine Resource and Utilization for Ministry of Education, School of Pharmacy, Shihezi University, Shihezi, China.
Abstract:
Two new phenolic glycosides, named lanatusosides C (1) and D (2), together with four known compounds (3-6), were isolated from the seeds of Citrullus lanatus. Among them, compounds 3 and 4 were isolated from Cucurbitaceae for the first time, and compound 5 was reported from this plant for the first time. Their structures were elucidated by means of extensive spectral analysis, including HR-ESI-MS, 1H and 13C NMR techniques. The isolated new compounds were evaluated for cytotoxic activity against HepG2 cell line, of which compound 1 demonstrated weak cytotoxicity against the tested cell line.
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