Related Experiment Video
Updated: Jan 31, 2026

Author Spotlight: Investigating HR-Dependent Cardiac Function in Mouse Models Through a Novel Atrial-Pacing Approach
Published on: July 21, 2023
Numerical Validation of Two-Parameter Weibull Model for Assessing Failure Fatigue Lives of Laminated Cementitious
Asad Hanif1, Yongjae Kim2, Cheolwoo Park3
1Department of Civil Engineering, Mirpur University of Science and Technology (MUST), Allama Iqbal Road Mirpur AJ&K, Mirpur 10250, Pakistan. ahanif@connect.ust.hk.
Abstract:
In this paper, comparative assessment of failure fatigue lives of thin laminated cementitious composites (LCCs) modeled by two modeling approaches-double-parameter Weibull distribution model and triple-parameter distribution model-was carried out. LCCs were fabricated of ordinary Portland cement (OPC), fly ash cenosphere (FAC), quartz sand, and reinforcing meshes and fibers. The failure fatigue life assessment at various probabilities by the two-parameter model was based on numerical calculations whereas the three-parameter model was applied by an open source program-ProFatigue®. Respective parameters, shape and scale parameters in the two-parameter Weibull distribution model while shape, scale, and location parameters in three-parameter model were determined, and the corresponding probabilistic fatigue lives at various failure probabilities were calculated. It is concluded that the two-parameter model is more accurate in probabilistic fatigue life assessment of double-layer mesh-reinforced LCCs, whereas for single-layer reinforced LCCs, both models could be used at a fair confidence level.
Related Concept Videos
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Model Approaches for Pharmacokinetic Data: Physiological Models
Model Approaches for Pharmacokinetic Data: Compartment Models
Two primary types of compartment models are recognized: mammillary and catenary. The more...
Parameters Affecting Nonlinear Elimination: Zero-Order Input, First-Order Absorption and Two-Compartment Model
When a drug is administered through a constant intravenous infusion and eliminated via nonlinear pharmacokinetics, it follows zero-order input. For example, oral drugs undergo first-order absorption upon administration and are eliminated through nonlinear pharmacokinetics.
In the case of subcutaneously administered drugs,...
Analysis Methods of Pharmacokinetic Data: Model and Model-Independent Approaches
The model approach uses mathematical models to describe changes in drug concentration over time. Pharmacokinetic models help characterize drug behavior in patients, predict drug concentration in the body fluids, calculate optimum dosage regimens, and evaluate the risk of toxicity. However, ensuring that the model fits the experimental data accurately...

