Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Phase Transitions02:31

Phase Transitions

23.1K
Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to...
23.1K
Properties of Transition Metals02:58

Properties of Transition Metals

29.8K
Transition metals are defined as those elements that have partially filled d orbitals. As shown in Figure 1, the d-block elements in groups 3–12 are transition elements. The f-block elements, also called inner transition metals (the lanthanides and actinides), also meet this criterion because the d orbital is partially occupied before the f orbitals.
29.8K
Cooperative Allosteric Transitions01:58

Cooperative Allosteric Transitions

8.7K
Cooperative allosteric transitions can occur in multimeric proteins, where each subunit of the protein has its own ligand-binding site. When a ligand binds to any of these subunits, it triggers a conformational change that affects the binding sites in the other subunits; this can change the affinity of the other sites for their respective ligands. The ability of the protein to change the shape of its binding site is attributed to the presence of a mix of flexible and stable segments in the...
8.7K
Phase Transitions: Vaporization and Condensation02:39

Phase Transitions: Vaporization and Condensation

21.2K
The physical form of a substance changes on changing its temperature. For example, raising the temperature of a liquid causes the liquid to vaporize (convert into vapor). The process is called vaporization—a surface phenomenon. Vaporization occurs when the thermal motion of the molecules overcome the intermolecular forces, and the molecules (at the surface) escape into the gaseous state. When a liquid vaporizes in a closed container, gas molecules cannot escape. As these gas phase molecules...
21.2K
Phase Transitions: Sublimation and Deposition02:33

Phase Transitions: Sublimation and Deposition

20.1K
Some solids can transition directly into the gaseous state, bypassing the liquid state, via a process known as sublimation. At room temperature and standard pressure, a piece of dry ice (solid CO2) sublimes, appearing to gradually disappear without ever forming any liquid. Snow and ice sublimate at temperatures below the melting point of water, a slow process that may be accelerated by winds and the reduced atmospheric pressures at high altitudes. When solid iodine is warmed, the solid sublimes...
20.1K
Phase Transitions: Melting and Freezing02:39

Phase Transitions: Melting and Freezing

15.1K
Heating a crystalline solid increases the average energy of its atoms, molecules, or ions, and the solid gets hotter. At some point, the added energy becomes large enough to partially overcome the forces holding the molecules or ions of the solid in their fixed positions, and the solid begins the process of transitioning to the liquid state or melting. At this point, the temperature of the solid stops rising, despite the continual input of heat, and it remains constant until all of the solid is...
15.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Self-assembled chamber-like cardiac organoids for modeling cardiac chamber formation and cardiotoxicity assessment.

Nature communications·2026
Same author

Developmental chronology of mouse embryo from 2-cell stage through birth.

Nature cell biology·2026
Same author

Recurrence in the chemotherapy regimen of bladder carcinoma originates from quiescent epidermoid-like cells.

Nature communications·2026
Same author

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity.

FEBS letters·2026
Same author

Chromatin Accessibility Dynamics during Chemical Induction of Pluripotency.

Cell stem cell·2026
Same author

In vitro mimicking of humanized cardiogenesis under porcine condition.

Cell & bioscience·2026
Same journal

Author Correction: Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance.

Nature cell biology·2026
Same journal

An atlas of primate insular cortex reveals a signal-processing strategy in von Economo neurons.

Nature cell biology·2026
Same journal

Primate neurons with special signalling logic.

Nature cell biology·2026
Same journal

Cell surface liposome binding (CLiB) allows lipid-binding probe engineering via high-throughput screening.

Nature cell biology·2026
Same journal

Mapping the human female reproductive tract.

Nature cell biology·2026
Same journal

Learning from stem cell-based embryo models.

Nature cell biology·2026
See all related articles

Related Experiment Video

Updated: Jan 31, 2026

Induction and Analysis of Epithelial to Mesenchymal Transition
10:37

Induction and Analysis of Epithelial to Mesenchymal Transition

Published on: August 27, 2013

36.5K

Mesenchymal-epithelial transition in development and reprogramming.

Duanqing Pei1,2, Xiaodong Shu3,4, Ama Gassama-Diagne5,6

  • 1CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. pei_duanqing@gibh.ac.cn.

Nature Cell Biology
|January 4, 2019
PubMed
Summary
This summary is machine-generated.

Mesenchymal-epithelial transition (MET) generates epithelial cells and is key for development and reprogramming. This review explores MET

More Related Videos

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
11:42

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

9.9K
Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
11:48

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition

Published on: October 9, 2014

13.4K

Related Experiment Videos

Last Updated: Jan 31, 2026

Induction and Analysis of Epithelial to Mesenchymal Transition
10:37

Induction and Analysis of Epithelial to Mesenchymal Transition

Published on: August 27, 2013

36.5K
Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells
11:42

Induction of Mesenchymal-Epithelial Transitions in Sarcoma Cells

Published on: April 7, 2017

9.9K
Detection of Alternative Splicing During Epithelial-Mesenchymal Transition
11:48

Detection of Alternative Splicing During Epithelial-Mesenchymal Transition

Published on: October 9, 2014

13.4K

Area of Science:

  • Cell Biology
  • Developmental Biology
  • Stem Cell Biology

Background:

  • Epithelial-mesenchymal transition (EMT) generates mesenchymal cells from epithelial cells.
  • Mesenchymal-epithelial transition (MET) is the reverse process, generating epithelial cells.
  • Both EMT and MET are crucial during organogenesis and in the induction of pluripotent stem cells.

Purpose of the Study:

  • To review the less characterized process of mesenchymal-epithelial transition (MET).
  • To focus on the role of MET in the genesis of apicobasal cell polarity.
  • To explore the broader roles of MET in development and cellular reprogramming.

Main Methods:

  • Literature review of existing studies on MET.
  • Analysis of molecular mechanisms underlying MET.
  • Synthesis of findings on MET's role in development and reprogramming.

Main Results:

  • MET is essential for restoring epithelial characteristics, including apicobasal polarity.
  • MET plays critical roles in embryonic development and tissue regeneration.
  • MET is a key factor in induced pluripotent stem cell (iPSC) generation.

Conclusions:

  • MET is a fundamental biological process with significant implications.
  • Understanding MET is vital for advancing developmental biology and regenerative medicine.
  • Further research into MET mechanisms can unlock new therapeutic strategies.