Related Experiment Video
Updated: Jan 31, 2026

Induction and Analysis of Epithelial to Mesenchymal Transition
Published on: August 27, 2013
Mesenchymal-epithelial transition in development and reprogramming
Duanqing Pei1,2, Xiaodong Shu3,4, Ama Gassama-Diagne5,6
1CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China. pei_duanqing@gibh.ac.cn.
Abstract:
During organogenesis, epithelial cells can give rise to mesenchymal cells through epithelial-mesenchymal transition. The reverse process, mesenchymal-epithelial transition (MET), can similarly generate epithelial cells. Transitions between epithelial and mesenchymal states are also critical for the induction of pluripotent stem cells from somatic cells. This Review discusses the relatively less characterized process of MET, focusing on the genesis of apicobasal cell polarity and exploring the roles of MET in development and reprogramming.
Related Concept Videos
Phase Transitions
Properties of Transition Metals
Cooperative Allosteric Transitions
Phase Transitions: Vaporization and Condensation
Phase Transitions: Sublimation and Deposition
Phase Transitions: Melting and Freezing

