Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hypertension: the sodium connection.

M H Weinberger1

  • 1Hypertension Research Center, Indiana University School of Medicine, Indianapolis.

Clinical Physiology and Biochemistry
|January 1, 1988
PubMed
Summary

Sodium intake can increase blood pressure and cardiovascular risks in susceptible individuals. Certain populations, like older adults and Black individuals, are more prone to sodium sensitivity, impacting hypertension development.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Achieving blood pressure goal: initial therapy with valsartan/hydrochlorothiazide combination compared with monotherapy.

Journal of human hypertension·2010
Same author

Antihypertensive therapy with aliskiren.

Kidney international·2007
Same author

Comprehensive suppression of the renin-angiotensin-aldosterone system in chronic kidney disease: covering all of the bases.

Kidney international·2006
Same author

Salt and blood pressure: What's new?

Current hypertension reports·2001
Same author

Salt sensitivity, pulse pressure, and death in normal and hypertensive humans.

Hypertension (Dallas, Tex. : 1979)·2001
Same author

Salt and blood pressure.

Current opinion in cardiology·2001

Area of Science:

  • Cardiovascular Science
  • Hypertension Research
  • Nutritional Epidemiology

Background:

  • Sodium intake is a known factor in elevating blood pressure and associated cardiovascular risks.
  • Potassium levels can be affected by sodium loading, potentially influencing blood pressure responses.
  • Certain demographics, including Black individuals, older adults, and those over 40, exhibit reduced sodium handling efficiency and are at higher risk for hypertension.

Purpose of the Study:

  • To explore the relationship between sodium intake, blood pressure regulation, and cardiovascular health.
  • To investigate the concept of sodium sensitivity versus resistance in different populations.
  • To identify potential predictors of sodium sensitivity.

Main Methods:

  • Review of epidemiologic, population, and individual studies on sodium and blood pressure.
  • Analysis of sodium handling efficiency in various demographic groups.
  • Assessment of methods for identifying sodium sensitivity, including rapid sodium/volume changes and dietary modifications.

Main Results:

  • Sodium intake is linked to increased blood pressure and cardiovascular complications in susceptible individuals.
  • Populations at higher risk for hypertension demonstrate less efficient sodium handling and are more sodium-sensitive.
  • Sodium sensitivity can be identified through physiological challenges and dietary sodium reduction.

Conclusions:

  • Sodium sensitivity is a key factor in hypertension development, particularly in at-risk populations.
  • Understanding sodium handling is crucial for managing blood pressure and cardiovascular disease.
  • Genetic markers and demographic factors may predict an individual's sodium sensitivity.

Related Experiment Videos