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Vesiculobullous cutaneous lymphatic reflux.

J W Groff1, J W White

  • 1Department of Dermatology, USAF Medical Center, Lackland Air Force Base, Texas.

Cutis
|July 1, 1988
PubMed
Summary
This summary is machine-generated.

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Cutaneous vesicles and bullae are rare in lymphedema. This case report details a patient with cervical cancer-related secondary lymphedema who developed these blistering lesions due to lymphatic fluid reflux.

Area of Science:

  • Oncology
  • Dermatology
  • Lymphatic Medicine

Background:

  • Lymphedema, a common condition, can present with rare cutaneous manifestations.
  • Secondary lymphedema often arises after cancer treatment, such as radiation therapy for cervical adenocarcinoma.

Observation:

  • A patient with cervical cancer treated with radiation developed acute secondary lymphedema.
  • The lymphedema was characterized by the sudden appearance of clear vesicles and bullae on the skin.

Findings:

  • Histopathology confirmed subepidermal vesicles directly connected to dermal lymphatic vessels.
  • These vesiculobullous lesions are specifically associated with acute-onset lymphedema.

Implications:

  • Vesiculobullous lymphatic reflux is a rare but significant complication of lymphedema.

Related Experiment Videos

  • This condition should be considered in the differential diagnosis of blistering skin diseases, particularly in patients with lymphedema.