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Serum uric acid and high-risk pregnancy: an intriguing correlation in advanced pregnant women
You-Fan Peng1, Xiang-Hui Su2, Man-Man Han1
1Department of Endocrinology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing 210009, China.
Background:
The aim of our study is to explore the relationship between serum uric acid (UA) and high-risk pregnancy (HRP) in advanced pregnant women.
Methods:
The study included 226 advanced pregnant women (≥35 years), and the HRP score were assessed according to China HRP score standards.
Results:
All data were separated into the three groups according to HRP score, we observed significant increases of serum UA concentrations between the three groups (207.51±42.45; 226.65±45.42 and 228.27±49.70 µmol/L, P=0.017). Notably, serum UA concentrations were found to be positive correlated with HRP score (r=0.165, P=0.013) in advanced pregnant women. Serum UA was independent correlated with HRP score (beta =0.164, P=0.009) in multiple linear regression analysis.
Conclusions:
We conclude that serum UA is correlated with HRP score, and increased serum UA levels may herald HRP in advanced pregnant women.
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