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Autoantibody to human c-myc oncogene product in autoimmune patients' sera
Y Deguchi1, S Negoro, S Kishimoto
1Third Department of Internal Medicine, Osaka University School of Medicine, Japan.
International Archives of Allergy and Applied Immunology
|January 1, 1988
Abstract:
Sera from autoimmune diseases including systemic lupus erythematosus, dermatomyositis, progressive systemic sclerosis and Sjögren's disease, were examined for reactivity against human c-myc oncogene product. We first found the presence of the autoantibody to human c-myc oncogene product in sera from autoimmune diseases. No significant correlation between the presence of the anti-c-myc product antibody and disease activity, clinical disease types and other autoantibodies such as antinuclear factor, anti-DNA antibody, anti-RNP antibody and anti-Sm antibody were shown in this study.