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Updated: Jan 31, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
Cetuximab in combination with chemoradiotherapy for nasopharyngeal carcinoma: A meta-analysis
Na Wang1, Kai Wang2, Feixue Song1
1Department of Oncology, Second Hospital of Lanzhou University, Lanzhou, Gansu Province, China.
Aims And Objectives:
The aims and objectives of this study are to investigate the efficacy and safety of chemoradiotherapy (CCRT) with or without cetuximab in nasopharyngeal carcinoma (NPC).
Methods:
We searched the Cochrane Library, PubMed, Embase, CNKI, VIP, Chinese biomedicine literature database, and WANFANG database for relevant articles. The methodological quality of included studies was evaluated, and data were analyzed using RevMan 5.0 software.
Results:
Ten relevant articles (783 patients) were identified. The results were complete response rate; the response rate was significantly better in the cetuximab plus CCRT (C225+CCRT) group than the CCRT group. The partial response and 3-year-overall survival rates were not significantly different between the two groups. Regarding adverse effects, myelosuppression was observed in the CRRT group and the C225+CCRT group; the main toxicity was mucositis and rash, but no significant statistical difference was observed.
Conclusion:
The combination of cetuximab and CCRT was more effective for NPC than CCRT alone and had no serious side effects.
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