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Updated: Oct 5, 2026
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FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
A simplified method for fixation of human and mouse preimplantation embryos which facilitates G-banding and
1Human Reproduction Unit, Royal North Shore Hospital, St Leonards, N.S.W., Australia.
Human Reproduction (Oxford, England)
|November 1, 1988
Abstract:
A reliable method for the fixation of large numbers of preimplantation embryos was developed to allow application of routine G-banding methods to preimplantation stage embryos. The technique resulted in minimal loss of embryos and was suitable for both 1-cell mouse embryos and multi-pronuclear human embryos. Application of this method will increase the information gained from chromosome studies of embryonic development.
