Related Experiment Video
Updated: Jan 31, 2026

Fully Autonomous Characterization and Data Collection from Crystals of Biological Macromolecules
Published on: March 22, 2019
Survey of the analysis of continuous conformational variability of biological macromolecules by electron microscopy
C O S Sorzano1, A Jiménez1, J Mota1
1National Center of Biotechnology (CSIC), Spain.
Abstract:
Single-particle analysis by electron microscopy is a well established technique for analyzing the three-dimensional structures of biological macromolecules. Besides its ability to produce high-resolution structures, it also provides insights into the dynamic behavior of the structures by elucidating their conformational variability. Here, the different image-processing methods currently available to study continuous conformational changes are reviewed.
Related Concept Videos
Surveys
Variability: Analysis
The range is a simple measure of variability, indicating the difference between the highest and...
¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR
Conformity
Introduction to Surveying, Plane Surveying and Geodetic Surveys
Overview of Electron Microscopy

