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Drebrin-Homer Interaction at An Atomic Scale
1Department of Pharmacology, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan.
In this issue of Structure, Li et al. (2018) describe a crystallographic view of the Drebrin-Homer interaction, mediated by the Homer binding motif of Drebrin and EVH1 domain of Homer. This interaction enables cross-linking of monomeric Drebrin by tetrameric Homer, which is required for efficient F-actin bundling.
In this issue of Structure, Li et al. (2018) describe a crystallographic view of the Drebrin-Homer interaction, mediated by the Homer binding motif of Drebrin and EVH1 domain of Homer. This interaction enables cross-linking of monomeric Drebrin by tetrameric Homer, which is required for efficient F-actin bundling.
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