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Default mode network alterations in individuals with high-trait-anxiety: An EEG functional connectivity study
Claudio Imperatori1, Benedetto Farina1, Mauro Adenzato2
1Department of Human Sciences, European University of Rome, Rome, Italy.
Individuals with high trait anxiety show reduced Default Mode Network (DMN) functional connectivity during rest. This suggests a potential cognitive control deficit, offering insights into trait anxiety's brain network differences.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Science
Background:
- Previous research explored Default Mode Network (DMN) alterations in anxiety disorders.
- Limited studies investigated DMN functional connectivity in non-clinical high-trait-anxiety individuals using electroencephalography (EEG).
Purpose of the Study:
- To investigate the association between trait anxiety and DMN EEG functional connectivity in non-clinical individuals.
- To extend previous findings on trait anxiety and DMN connectivity.
Main Methods:
- Quantitative electroencephalography (EEG) was used to record resting-state brain activity.
- eLORETA software analyzed DMN functional connectivity in individuals with high-trait-anxiety and controls.
- Twenty-three high-trait-anxiety individuals and twenty-four controls participated.
Main Results:
- High-trait-anxiety individuals exhibited decreased theta connectivity between the right medial prefrontal cortex (mPFC) and right posterior cingulate/retrosplenial cortex.
- Reduced beta connectivity was observed between the right mPFC and right anterior cingulate cortex in the high-trait-anxiety group.
- DMN functional connectivity strength was negatively correlated with trait anxiety scores.
Conclusions:
- High-trait-anxiety individuals may fail to synchronize their DMN during resting state.
- This desynchronization could indicate a top-down cognitive control deficit.
- Findings contribute to understanding individual differences in brain networks related to trait anxiety.
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