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Disseminated canine mold infections
1Department of Clinical Bacteriology and Mycology, The Kimron Veterinary Institute, Bet Dagan, Israel.
Veterinary Journal (London, England : 1997)
|January 5, 2019
Summary
Disseminated mold infections in dogs are often caused by Aspergillus, particularly in German Shepherds. Treatment is challenging, with frequent relapses, highlighting the need for better diagnostics and therapies for canine mycoses.
Area of Science:
- Veterinary Mycology
- Canine Infectious Diseases
Background:
- Disseminated mold infections pose a significant threat to canine health.
- Understanding the prevalence and causative agents is crucial for effective management.
Purpose of the Study:
- To review cases of disseminated mold infections in dogs.
- To identify common etiological agents, host factors, clinical signs, and treatment outcomes.
Main Methods:
- Systematic review of 157 canine cases with disseminated mold infections.
- Analysis of etiological agents, breed, sex, age, clinical signs, laboratory findings, and treatment responses.
Main Results:
- Aspergillus spp. caused 59.3% of infections, with section Terrei being prevalent (36.3%).
- German Shepherds (67.8%) were most affected, predominantly by section Terrei Aspergillus.
- Common signs included weight loss, lethargy, discospondylitis, and osteomyelitis; treatment success was limited with frequent relapses.
Conclusions:
- Aspergillus spp., particularly section Terrei, are major causes of disseminated mycoses in dogs, especially German Shepherds.
- Current treatments have limited success, emphasizing the need for improved diagnostics, genetic predisposition identification, and novel therapeutic strategies.
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