Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Histone Modification02:32

Histone Modification

16.1K
The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone...
16.1K
Histone Modification02:32

Histone Modification

4.5K
4.5K
Spreading of Chromatin Modifications02:25

Spreading of Chromatin Modifications

9.5K
The histone proteins in the nucleosomes are post-translationally modified (PTM) to increase or decrease access to DNA. The commonly observed PTMs are methylation, acetylation, phosphorylation, and ubiquitination of lysine amino acids in the histone H3 tail region. These histone modifications have specific meaning for the cell. Hence, they are called "histone code". The protein complex involved in histone modification is termed as "reader-writer" complex.
Writers
The writer...
9.5K
Behavior Modification01:21

Behavior Modification

692
Behavioral approaches have often been criticized for ignoring mental processes and focusing solely on observable behavior. However, these approaches provide an optimistic perspective for individuals seeking to change their behaviors. Rather than concentrating on intrinsic personality traits, behavioral approaches suggest that even longstanding habits can be modified by changing the reward contingencies that maintain them.
A real-world application of operant conditioning principles is applied...
692
Self-Evaluation: Self-Enhancement and Self-Verification03:00

Self-Evaluation: Self-Enhancement and Self-Verification

5.8K
Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
5.8K
Physical and Chemical Properties of Matter02:57

Physical and Chemical Properties of Matter

166.3K
The characteristics that enable us to distinguish one substance from another are called properties.
166.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fast hydrated-ion transport and desolvation in pyridinyl COF membranes <i>via</i> competitive coordination.

Chemical science·2026
Same author

Tailoring Biomass-Derived Organosolv Lignin Derivatives for High-Capacity Adsorption of Rhodamine B.

ChemSusChem·2026
Same author

Retraction notice to "Corrigendum to "Impact of polymer chemistry on critical quality attributes of selective laser sintering 3D printed solid oral dosage forms" [International Journal of Pharmaceutics:X Volume 6 (2023) 100203] [International Journal of Pharmaceutics: X 9 (2025) 100319].

International journal of pharmaceutics: X·2026
Same author

Waveguide Spectroscopy for Differentiation of Bacteria.

Analytical chemistry·2025
Same author

Geometry impact on fundamental properties of theophylline-containing SLS printed pharmaceutical tablets.

Frontiers in drug delivery·2025
Same author

Scalable and Versatile Fabrication of Free-Standing Covalent Organic Framework Membranes with Tunable Microstructure for Molecular Separation.

Journal of the American Chemical Society·2025

Related Experiment Video

Updated: Jan 31, 2026

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
11:19

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

10.7K

Titanium surface modification to enhance antibacterial and bioactive properties while retaining biocompatibility.

Oscar Janson1, Satwik Gururaj1, Shiuli Pujari-Palmer1

  • 1Division of Applied Material Science, Department of Engineering Sciences, The Ångström Laboratory, Uppsala University, Sweden.

Materials Science & Engineering. C, Materials for Biological Applications
|January 5, 2019
PubMed
Summary

This study developed a novel surface treatment for titanium implants to prevent bacterial infections. The multi-step process enhances bioactivity and biocompatibility without using antibiotics, offering a promising solution for implant-associated infections.

Keywords:
AntibacterialBioactivityCalcium titanateCell viabilitySodium titanateTitanium

More Related Videos

Surface Properties of Synthesized Nanoporous Carbon and Silica Matrices
09:31

Surface Properties of Synthesized Nanoporous Carbon and Silica Matrices

Published on: March 27, 2019

10.0K
Production of Metal Nanoparticles by Pulsed Laser-ablation in Liquids: A Tool for Studying the Antibacterial Properties of Nanoparticles
07:40

Production of Metal Nanoparticles by Pulsed Laser-ablation in Liquids: A Tool for Studying the Antibacterial Properties of Nanoparticles

Published on: June 2, 2017

15.7K

Related Experiment Videos

Last Updated: Jan 31, 2026

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties
11:19

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

10.7K
Surface Properties of Synthesized Nanoporous Carbon and Silica Matrices
09:31

Surface Properties of Synthesized Nanoporous Carbon and Silica Matrices

Published on: March 27, 2019

10.0K
Production of Metal Nanoparticles by Pulsed Laser-ablation in Liquids: A Tool for Studying the Antibacterial Properties of Nanoparticles
07:40

Production of Metal Nanoparticles by Pulsed Laser-ablation in Liquids: A Tool for Studying the Antibacterial Properties of Nanoparticles

Published on: June 2, 2017

15.7K

Area of Science:

  • Biomaterials Science
  • Infectious Disease Research
  • Surface Chemistry

Background:

  • Bacterial infections pose significant risks for patients with dental and orthopedic implants.
  • Developing effective strategies to prevent implant-associated infections is crucial for patient outcomes.
  • Commercially pure titanium grade 2 is widely used in biomedical implants.

Purpose of the Study:

  • To investigate the antibacterial, bioactive, and biocompatible properties of a modified titanium surface.
  • To optimize a multi-step surface modification procedure for titanium implants.
  • To evaluate a non-antibiotic approach for preventing implant infections.

Main Methods:

  • Surface modification of titanium grade 2 using hydrogen peroxide, sodium hydroxide, and calcium hydroxide.
  • Testing antibacterial effects against Staphylococcus epidermidis (direct contact and biofilm inhibition).
  • Assessing biocompatibility using human dermal fibroblast and MC3T3 pre-osteoblast cells.

Main Results:

  • Hydrogen peroxide treatment alone showed antibacterial activity but lacked bioactivity and biocompatibility.
  • Subsequent treatments with sodium hydroxide and calcium hydroxide enhanced bioactivity and biocompatibility.
  • Autoclaving further improved bioactivity, indicating a promising multi-step modification strategy.

Conclusions:

  • A multi-step surface modification of titanium implants can provide antibacterial properties while enhancing bioactivity and biocompatibility.
  • This approach offers a non-antibiotic alternative for preventing infections associated with biomedical implants.
  • The developed surface treatment shows potential for improving the safety and efficacy of dental and orthopedic implants.