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Cellulose/vaterite nanocomposites: Sonochemical synthesis, characterization, and their application in protein
Lian-Hua Fu1, Chao Qi1, Yan-Ru Hu1
1Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060, PR China.
Abstract:
Vaterite is recognized as an important biomedical material owing to its features such as high specific surface area, high solubility, high dispersion, and small specific gravity. Herein, we report a facile and green sonochemical route to prepare vaterite nanospheres (assembled from rice-shaped nanoparticles) with average diameter of 206-246 nm by using cellulose as substrate. The important role of cellulose concentration on the phase of the products was systematically investigated, and the formation mechanism of vaterite was proposed. Moreover, the as-prepared cellulose/vaterite nanocomposites have a good cytocompatibility and a relatively high protein adsorption ability using hemoglobin as a model protein. These results indicate that the as-prepared cellulose/vaterite nanocomposites are promising for applications in biomedical fields, such as protein adsorption.
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