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Updated: Jan 31, 2026

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
Published on: April 13, 2022
Chitosan and its derivatives: synthesis, biotechnological applications, and future challenges
Muhammad Shahid Riaz Rajoka1,2, Liqing Zhao3, Hafiza Mahreen Mehwish4
1Department of Food Science and Engineering, College of Chemistry and Environmental Engineering, Shenzhen University, Shenzhen, Guangdong, People's Republic of China.
Abstract:
Chitosan is a naturally occurring biodegradable as well as a non-toxic polymer generated from chitin through alkaline deacetylation reaction, and it is insoluble in organic/inorganic solvents and water. Furthermore, chitosan is one of the most plentiful cationic polymers in natural surroundings. Due to its non-toxicity and biocompatibility, chitosan is extensively employed in industrial, biomedical, food, pharmaceutical, environmental, and agricultural industry. Chitosan-based biomaterials exhibit great potential in various biotechnological applications, such as anti-hypertensive therapy, anti-oxidant, anti-microbial, anti-allergic, immunostimulant, cancer therapy, delivery of genetic materials, delivery of bone morphogenetic type-2, wound healing, treatment of wastewater, hypocholesterolemic, and bio-imaging. Therefore, this review mainly focuses on the biotechnological potential of chitosan and its derivatives as well as presents the potential of chitosan-based biomaterial/pharmaceutical for the prevention of various life-threating chronic disorders.
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