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In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
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Tuberculosis and Takayasu arteritis: case-based review.

Moritz K Jansson1, Hilte F Geerdes-Fenge2, Antje Kangowski3

  • 1Department of Tropical Medicine and Infectious Diseases, Rostock University Medical Center, Ernst-Heydemann-Str. 6, 18057, Rostock, Germany. moritz.jansson@uni-rostock.de.

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|January 5, 2019
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Summary
This summary is machine-generated.

Takayasu arteritis (TA) and multiorgan tuberculosis (TB) can co-occur, particularly in young patients. Management often involves antituberculous therapy and corticosteroids, but relapses of TA may require further immunosuppression.

Keywords:
Autoimmune diseaseTakayasu arteritisTuberculosisTuberculosis, Lymph nodeVasculitis

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Area of Science:

  • Rheumatology
  • Infectious Diseases
  • Vascular Inflammation

Background:

  • Takayasu arteritis (TA) is a rare, chronic inflammatory disease affecting large arteries.
  • Tuberculosis (TB) is an infectious disease with diverse clinical presentations.
  • Co-occurrence of TA and TB presents diagnostic and therapeutic challenges.

Observation:

  • A case of co-occurring Takayasu arteritis and multiorgan tuberculosis in a 20-year-old female is reported.
  • A review of 18 previously reported cases of concomitant TA and TB is included.
  • Patients ranged from 9 to 24 years of age, with most diagnosed with active TB and TA concurrently.

Findings:

  • TB lymphadenitis was the most common TB manifestation (57.9%).
  • Antituberculous therapy and corticosteroids were standard treatments (89.5% received corticosteroids).
  • TA relapses requiring additional immunosuppressive therapy were noted in some cases.

Implications:

  • Concurrent TA and TB necessitates careful diagnostic evaluation and tailored treatment strategies.
  • Long-term monitoring for TA relapses is crucial in patients treated for both conditions.
  • Understanding the interplay between these diseases can improve patient outcomes.