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Updated: Jan 31, 2026

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
Published on: March 11, 2016
[Renal dysfunction and indicators of arterial hormity in persons of elderly and senile age.]
I T Murkamilov1,2, I S Sabirov2, K A Aitbaev3
1I.K.Akhunbaev Kyrgyz State Medical Academy, 92, Akhunbaev str., Bishkek, 720020, Kyrgyzstan;
Abstract:
In the presented paper had been examined parameters of arterial stiffness (stiffness index, SI m/s; reflection index, RI%; augmentation index, Alp; biological age of the vascular system, VA years; age index, AGI; alternative stiffness index, aSI; index of increase in HP=75, Aiр 75%), central arterial pressure and cystatin C content in serum. A totally were examined 98 persons (women, n=45 and men, n=53) elderly and older. A comparative analysis of arterial stiffness and its relationship with blood cystatin C in the examined groups with gender differences taken into account. In the elderly and older women, the augmentation index and its increase at a pulse rate of 75, atherogenic lipids (total cholesterol, low-density lipoprotein cholesterol and serum triglycerides) were significantly higher, and the indicators of the alternative stiffness index were significantly lower compared to men elderly and older. The greatest number of correlation interrelations was found between the indices of arterial stiffness and the level of cystatin C in the group of women of elderly and senile age.
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