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Umbilical cord pseudocyst in trisomy 18.
E Jauniaux1, C Donner, C Thomas
1Departments of Obstetrics and Gynecology, Hôpital Universitaire Erasme, Bruxelles, Belgium.
Prenatal Diagnosis
|October 1, 1988
Summary
Prenatal ultrasound can accurately diagnose umbilical cord defects. Two cases of umbilical cord pseudocysts linked to trisomy 18 highlight the need for karyotyping and careful examination of affected fetuses and newborns.
Area of Science:
- Obstetrics and Gynecology
- Fetal Medicine
- Medical Genetics
Background:
- Prenatal diagnosis of umbilical cord anomalies is crucial for fetal well-being.
- Ultrasound examination offers high accuracy in detecting fetal structural abnormalities.
- Umbilical cord pseudocysts are rare findings during prenatal imaging.
Observation:
- Two cases of fetal umbilical cord pseudocysts were identified via ultrasound.
- Both cases were associated with trisomy 18, a significant chromosomal abnormality.
- This association suggests a potential link between cord defects and specific genetic conditions.
Findings:
- Prenatal ultrasound is effective in diagnosing umbilical cord pseudocysts.
- The presence of umbilical cord pseudocysts may indicate an increased risk of trisomy 18.
- Karyotyping via umbilical blood sampling is recommended for fetuses with such anomalies.
Implications:
- Early detection of umbilical cord anomalies aids in risk assessment for chromosomal disorders.
- Genetic analysis is essential for managing pregnancies with suspected fetal defects.
- Thorough examination of placentas and neonates is vital post-delivery for comprehensive assessment.