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Real-time Imaging of Heterotypic Platelet-neutrophil Interactions on the Activated Endothelium During Vascular Inflammation and Thrombus Formation in Live Mice
11:18

Real-time Imaging of Heterotypic Platelet-neutrophil Interactions on the Activated Endothelium During Vascular Inflammation and Thrombus Formation in Live Mice

Published on: April 2, 2013

Platelets and atherosclerosis

J C Hoak1

  • 1Department of Medicine, University of Iowa Hospitals Clinics, Iowa City 52242.

Seminars in Thrombosis and Hemostasis
|April 1, 1988
PubMed

This discussion has centered about the consequences of the loss of endothelial integrity and how the blood platelet behaves under these circumstances. It is clear that the platelet can function as a participant in the development of the atherosclerotic lesion, can be an important contribution to mechanisms that operate to produce vascular spasm, and ultimately can play a major role in the development of thrombosis at the site of the complicated end-stage atherosclerotic lesion.

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