Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Combined immunologic deficiency].

E J Gerritsen1, H van den Berg, R L Langlois van den Bergh

  • 1Afd. Kindergeneeskunde, Academisch Ziekenhuis, Leiden.

Tijdschrift Voor Kindergeneeskunde
|October 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Molecular-integrated risk profile to determine adjuvant radiotherapy in endometrial cancer: Evaluation of the pilot phase of the PORTEC-4a trial.

Gynecologic oncology·2018
Same author

A pan-European ring trial to validate an International Standard for detection of Vibrio cholerae, Vibrio parahaemolyticus and Vibrio vulnificus in seafoods.

International journal of food microbiology·2018
Same author

Multiple central giant cell tumour lesions are exclusively linked to syndromes related to RAS/MAPK pathway anomalies.

International journal of oral and maxillofacial surgery·2017
Same author

Investigating the heterogeneity of alkylating agents' efficacy and toxicity between sexes: A systematic review and meta-analysis of randomized trials comparing cyclophosphamide and ifosfamide (MAIAGE study).

Pediatric blood & cancer·2017
Same author

Seclusion and enforced medication in dealing with aggression: A prospective dynamic cohort study.

European psychiatry : the journal of the Association of European Psychiatrists·2016
Same author

Results of a pooled analysis of IOERT containing multimodality treatment for locally recurrent rectal cancer: Results of 565 patients of two major treatment centres.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2016

Severe combined immunodeficiency (SCID) is a heterogeneous disorder. Bone marrow transplantation offers a cure for most SCID patients, even without an HLA-identical donor.

Area of Science:

  • Immunology
  • Genetics
  • Pediatrics

Context:

  • Presents clinical and immunological findings of 32 severe combined immunodeficiency (SCID) patients treated over 20 years.
  • Discusses the recent WHO classification of combined immunodeficiency diseases.
  • Explores the known pathogenesis of various SCID forms.

Purpose:

  • To detail the clinical and immunological characteristics of SCID patients.
  • To discuss SCID classification and pathogenesis in light of recent findings.
  • To review the therapeutic efficacy of bone marrow transplantation (BMT) for SCID.

Summary:

  • Severe combined immunodeficiency (SCID) is a group of heterogeneous disorders.
  • Bone marrow transplantation (BMT) is the only curative treatment for SCID, with high success rates.

Related Experiment Videos

  • Advances in carrier detection and antenatal diagnosis are also considered.

    • Impact:

    • Highlights the heterogeneity of SCID, impacting diagnostic and therapeutic strategies.
    • Emphasizes the critical role of BMT in SCID treatment, offering hope for recovery.
    • Underscores the importance of early diagnosis and intervention for improved patient outcomes.