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Related Experiment Video

Updated: Jan 31, 2026

Isolating and Imaging Live, Intact Pacemaker Regions of Mouse Renal Pelvis by Vibratome Sectioning
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Tachycardia with alternating pacemaker spikes: Is it pacemaker malfunction?

Mahmoud Allahham1, Mark Pollet2, Jie Cheng3

  • 1Department of Medicine at Baylor College of Medicine, United States of America.

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|January 7, 2019
PubMed
Summary

A patient with multiple chronic conditions experienced tachycardia with alternating pacemaker spikes during a routine heart failure follow-up. This finding indicates a potential issue with the biventricular implantable cardioverter-defibrillator device or underlying cardiac rhythm.

Keywords:
Abnormal ECGAccelerated junctional rhythmBiventricular ICDBlanking periodDigoxin toxicityHeart failure

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Area of Science:

  • Cardiology
  • Biomedical Engineering

Background:

  • The patient is a 67-year-old female with a history of type 2 diabetes mellitus, chronic kidney disease, and ischemic cardiomyopathy.
  • She has a biventricular implantable cardioverter-defibrillator (CRT-D) in place for cardiac management.

Observation:

  • The patient presented for a routine follow-up appointment at the Heart Failure clinic.
  • During the visit, she exhibited tachycardia accompanied by alternating pacemaker spikes on electrocardiogram (ECG).

Findings:

  • The presence of tachycardia with alternating pacemaker spikes suggests a potential device malfunction or an inappropriate pacing response.
  • This could indicate lead dislodgement, battery depletion, or a programming issue with the CRT-D device.

Implications:

  • Urgent evaluation and troubleshooting of the biventricular implantable cardioverter-defibrillator are necessary to determine the cause of the observed anomaly.
  • Prompt intervention is crucial to prevent potential adverse cardiac events and ensure optimal device function in managing the patient's heart failure and underlying cardiac conditions.