Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Systems of Linear Equations in Two Variables01:25

Systems of Linear Equations in Two Variables

306
Solving a system of linear equations is a fundamental concept in algebra. A system of equations consists of two or more linear equations involving the same set of variables. One of the most efficient algebraic methods for solving such systems is the substitution method. This technique involves expressing one variable in terms of the other from one equation and substituting it into the second equation. This method is particularly useful when one of the equations is easily rearranged.Consider the...
306
Linear Circuits01:17

Linear Circuits

872
A linear circuit is characterized by its output having a direct proportionality to its input, adhering to the linearity property, which encompasses the principles of homogeneity (scaling) and additivity. Homogeneity dictates that when the input, also referred to as the excitation, is multiplied by a constant factor, the output, known as the response, is correspondingly scaled by the same constant factor. For instance, if the current is multiplied by a constant 'k,' the voltage likewise...
872
Variability: Analysis01:11

Variability: Analysis

509
Measures of variability are statistical metrics that reveal the dispersion pattern within a dataset. They are pivotal in biostatistics, providing insights into the heterogeneity within health and biological data. Variability signifies the degree to which data points diverge from one another, helping researchers understand the potential range of values and associated uncertainty within the data.
The range is a simple measure of variability, indicating the difference between the highest and...
509
Random Variables01:09

Random Variables

17.8K
A random variable is a single numerical value that indicates the outcome of a procedure. The concept of random variables is fundamental to the probability theory and was introduced by a Russian mathematician, Pafnuty Chebyshev, in the mid-nineteenth century.
Uppercase letters such as X or Y denote a random variable. Lowercase letters like x or y denote the value of a random variable. If X is a random variable, then X is written in words, and x is given as a number.
For example, let X = the...
17.8K
Linear Equations01:27

Linear Equations

475
Linear equations form the foundation of many algebraic and real-world applications, characterized by their simplicity and utility. A linear equation is an algebraic statement in which each term is either a constant or a product of a constant and a single variable. These equations represent straight lines when plotted on a Cartesian coordinate plane, reflecting a constant rate of change between two quantities.A typical linear equation in one variable has the form: ax + b = c, where a, b, and c...
475
Pharmacokinetic Models: Comparison and Selection Criterion01:26

Pharmacokinetic Models: Comparison and Selection Criterion

359
Physiological and compartmental models are valuable tools used in studying biological systems. These models rely on differential equations to maintain mass balance within the system, ensuring an accurate representation of the dynamic processes at play.
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.
359

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Triptolide protects rat heart against pressure overload-induced cardiac fibrosis.

International journal of cardiology·2013
Same author

Multiresidue pesticide analysis of botanical dietary supplements using salt-out acetonitrile extraction, solid-phase extraction cleanup column, and gas chromatography-triple quadrupole mass spectrometry.

Analytical chemistry·2013
Same author

Interaction domains of p62: a bridge between p62 and selective autophagy.

DNA and cell biology·2013
Same author

Predictors of seizure freedom after surgical management of tuberous sclerosis complex: a systematic review and meta-analysis.

Epilepsy research·2013
Same author

Temporary ileostomy versus colostomy for colorectal anastomosis: evidence from 12 studies.

Scandinavian journal of gastroenterology·2013
Same author

Localized leptin release may be an important mechanism of curcumin action after acute ischemic injuries.

The journal of trauma and acute care surgery·2013

Related Experiment Video

Updated: Jan 31, 2026

Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size LEfSe in Microbiome Data
04:57

Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size LEfSe in Microbiome Data

Published on: May 16, 2022

17.4K

Efficient test-based variable selection for high-dimensional linear models.

Siliang Gong1, Kai Zhang1, Yufeng Liu1,2

  • 1Department of Statistics and Operations Research, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, United States.

Journal of Multivariate Analysis
|January 8, 2019
PubMed
Summary
This summary is machine-generated.

A new test-based variable selection method offers a computationally efficient and statistically interpretable alternative to cross-validation for high-dimensional data analysis. This approach improves variable selection accuracy and reduces computational complexity.

Keywords:
Cross-validationHigh-dimensional testingMaximal absolute correlationVariable selection

More Related Videos

A Rapid Method for Modeling a Variable Cycle Engine
04:58

A Rapid Method for Modeling a Variable Cycle Engine

Published on: August 13, 2019

8.0K
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

8.1K

Related Experiment Videos

Last Updated: Jan 31, 2026

Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size LEfSe in Microbiome Data
04:57

Assisted Selection of Biomarkers by Linear Discriminant Analysis Effect Size LEfSe in Microbiome Data

Published on: May 16, 2022

17.4K
A Rapid Method for Modeling a Variable Cycle Engine
04:58

A Rapid Method for Modeling a Variable Cycle Engine

Published on: August 13, 2019

8.0K
A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

8.1K

Area of Science:

  • Statistics
  • Machine Learning
  • Data Science

Background:

  • Variable selection is crucial in high-dimensional data analysis.
  • Existing methods like Forward Stepwise Regression (FSR) and Least Angle Regression (LARS) often rely on cross-validation (CV) for stopping criteria.
  • Cross-validation (CV) suffers from high computational costs and lacks statistical interpretation.

Purpose of the Study:

  • To introduce a novel, flexible, and efficient test-based variable selection approach.
  • To overcome the limitations of computational expense and lack of statistical interpretation associated with cross-validation (CV).
  • To develop a stopping criterion for sequential variable selection procedures in high-dimensional settings.

Main Methods:

  • A new test is proposed based on maximal absolute partial correlation between inactive and response variables, conditional on active variables.
  • The asymptotic null distribution of the test statistic is derived for high dimensions.
  • The test is shown to be consistent, with variables added based on a pre-defined p-value threshold.

Main Results:

  • The proposed test-based method is incorporated into sequential selection procedures.
  • Numerical studies demonstrate competitive performance compared to cross-validation (CV).
  • The method shows strong variable selection accuracy and reduced computational complexity.

Conclusions:

  • The introduced test-based variable selection approach provides a viable and efficient alternative to cross-validation (CV).
  • This method enhances statistical interpretability while maintaining high performance in variable selection.
  • It offers a promising solution for analyzing high-dimensional data effectively.