Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[The locked-in syndrome].

J L Delacour1, C Floriot, G Wagschal

  • 1Service de Réanimation Polyvalente, Centre Hospitalier Paul-Morel, Vesoul.

Annales Francaises D'Anesthesie Et De Reanimation
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hemodynamic Surrogate Measures Symplifying Neurally Mediated Syncope Management.

Biomedizinische Technik. Biomedical engineering·2013
Same author

Vagal heart rate control in patients with atrial fibrillation: impact of tonic activation of peripheral chemosensory function in heart failure.

Advances in experimental medicine and biology·2012
Same author

Influence of age-related factors on long-term outcome after traumatic brain injury (TBI) in children: A review of recent literature and some preliminary findings.

Restorative neurology and neuroscience·2012
Same author

Assessment of sensorimotor functions after traumatic brain injury (TBI) in childhood - Methodological aspects.

Restorative neurology and neuroscience·2012
Same author

Ventricular tachycardia and sudden death after primary PCI-reperfusion therapy: impact on primary prevention of sudden cardiac death.

Herzschrittmachertherapie & Elektrophysiologie·2011
Same author

A decision tree to help determine the best timing and antiretroviral strategy in HIV-infected patients.

Epidemiology and infection·2011
Same journal

Annales francaises d'anesthesie et de reanimation·2020
Same journal

[Multimodal approach to enhance filter lifespan: are all actions equal?].

Annales francaises d'anesthesie et de reanimation·2014
Same journal

[Disparity of French Emergency medical services equipment: disparity of funding allocation or of management quality?].

Annales francaises d'anesthesie et de reanimation·2014
Same journal

[Eligibility to a Maastricht III - type organ donation according to the protocol proposed by the French organ procurement organization (Agence de la biomedicine) among patients in a medico surgical intensive care unit].

Annales francaises d'anesthesie et de reanimation·2014
Same journal

[Enhanced recovery after elective colorectal surgery: reply].

Annales francaises d'anesthesie et de reanimation·2014
Same journal

[Aorto-right atrial fistula as complication of aortic dissection].

Annales francaises d'anesthesie et de reanimation·2014
See all related articles

Locked-in syndrome involves complete paralysis but preserved consciousness, often misdiagnosed as coma. Early diagnosis and fibrinolytic therapy for vascular obstruction can be critical for these patients.

Area of Science:

  • Neurology
  • Critical Care Medicine

Context:

  • Locked-in syndrome (LIS) is a rare neurological condition characterized by profound immobility with preserved consciousness.
  • It is frequently misdiagnosed as coma, leading to delayed or inappropriate patient management.
  • Understanding the diverse etiologies and clinical presentations of LIS is crucial for timely intervention.

Purpose:

  • To highlight the diagnostic challenges and clinical features of locked-in syndrome.
  • To discuss the potential causes, including vascular obstruction, and the importance of early recognition.
  • To emphasize the necessity of intensive care and communication strategies for patients with LIS.

Summary:

  • LIS results in complete paralysis of voluntary muscles, excluding eye movements and blinking, while consciousness remains intact.

Related Experiment Videos

  • Vascular obstruction in the vertebral and basilar arteries is a primary cause, though etiological diversity exists.
  • Communication is possible through preserved vertical eye movements and blinking, enabling eye-code systems.

    • Impact:

    • Early diagnosis of vascular obstruction allows consideration of fibrinolytic therapy, potentially improving outcomes.
    • Intensive care, including tracheostomy and ventilation, is vital for patient survival.
    • Awareness among healthcare professionals that LIS patients are conscious and communicative is paramount for appropriate care and support.