Related Experiment Video
Updated: Jan 31, 2026

In Silico Clinical Trials for Cardiovascular Disease
Published on: May 27, 2022
Virtual TEVAR: Overcoming the Roadblocks of In-Silico Tools for Aortic Dissection Treatment
Vanessa Diaz-Zuccarini1,2, Mirko Bonfanti2,1, Gaia Franzetti1
1University College London, Department of Mechanical Engineering, Multiscale Cardiovascular Engineering Group, UK.
Abstract:
The use of in silico tools for the interventional planning of complex vascular conditions, such as Aortic Dissections has been often limited by high computational cost, involving long timescales for accurate results to be produced and low numbers of patients, precluding the use of statistical analyses to inform individual-level models. In the paper [Theranostics 2018; 8(20):5758-5771. doi:10.7150/thno.28944], Chen et al. proposed a novel algorithm to compute patient-specific 'virtual TEVAR' that will help clinicians to approach individual treatment and decision-making based on objective and quantifiable metrics and validated on a cohort of 66 patients in real time. This research will significantly impact the field and has the potential to transform the way clinical interventions will be approached in the future.
Related Concept Videos
Virtual Work
In static equilibrium, a body can experience an imaginary or virtual movement, such as displacement or rotation. The virtual work done by a force is equal to the dot product of force and virtual displacement in the direction of the force. When it comes to virtually rotating a...
Bioavailability Enhancement: Determination and Conceptual Approaches in Overcoming Bioavailability Problems
Principle of Virtual Work: Problem Solving
To apply the principle of virtual work,...
Virtual Work for a System of Connected Rigid Bodies
Next,...
Aortic Regurgitation I: Introduction
Aortic Regurgitation III: Medical Management

