Related Experiment Video
Updated: Jan 31, 2026
05:17
Author Spotlight: Enhancing the Offspring Health in Rats with Maternal Exercise During Pregnancy
Published on: April 5, 2024
1.4K
Exercise in Myositis.
1Department of NVS, Huddinge, Karolinska Institutet and Department of Medicine, Karolinska Institutet, Solna and Function Area Occupational Therapy and Physical Therapy, Karolinska University Hospital, SE-171 76 Stockholm, Sweden.
Current Treatment Options in Rheumatology
|January 8, 2019
Summary
Exercise is safe and effective for adult idiopathic inflammatory myopathies (IIM). Recent studies show intensive endurance exercise improves muscle growth and mitochondrial function, while blood-flow restricted training maintains strength in inclusion body myositis.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Exercise Physiology
Background:
- Idiopathic inflammatory myopathies (IIM) are chronic autoimmune diseases affecting muscles.
- Exercise is increasingly recognized as a crucial component of IIM management.
- Recent research focuses on specific exercise modalities and their effects in adult myositis.
Purpose of the Study:
- To review recent exercise studies (last 2 years) in adult myositis patients.
- To evaluate the efficacy and safety of various exercise interventions.
- To identify gaps in knowledge regarding exercise in active inflammatory myopathies.
Main Methods:
- Systematic review of exercise interventions in adult IIM.
- Analysis of studies on endurance training, resistance training, and combined therapies.
- Inclusion of studies examining novel treatments like follistatin in conjunction with exercise.
Main Results:
- Intensive endurance exercise demonstrated anti-inflammatory effects, promoting muscle growth and improving mitochondrial function.
- Blood-flow restricted resistance training preserved muscle strength in inclusion body myositis patients.
- Exercise, including in combination with follistatin, showed improved physical capacity, with higher exercise levels correlating with better outcomes.
Conclusions:
- Exercise is safe across all types and stages of myositis and can be considered a therapeutic intervention.
- Supervised, low-intensity exercise initiation with gradual progression is recommended.
- Further research is needed on exercise effects in active polymyositis and dermatomyositis.
Related Concept Videos
01:26Exercise Stress Test
1.3K
Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
1.3K
01:27Exercise and Muscle Performance
2.4K
Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
2.4K
01:17Exercise and Cardiac Output
1.9K
Regular physical activity is essential for maintaining cardiovascular health, with aerobic exercises being particularly effective. According to the American Heart Association, 150 minutes of moderate to intense aerobic exercise per week is recommended for a healthy heart. Aerobic activities may include brisk walking, running, bicycling, cross-country skiing, and swimming, ideally performed three to five times per week.
Sustained exercise increases the muscles' oxygen demand, which can be...
Sustained exercise increases the muscles' oxygen demand, which can be...
1.9K
01:20Exercise and Cardiovascular Response
4.5K
Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
4.5K
02:20Longitudinal Research
13.3K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.3K
01:29Fermentation
129.2K
Most eukaryotic organisms require oxygen to survive and function adequately. Such organisms produce large amounts of energy during aerobic respiration by metabolizing glucose and oxygen into carbon dioxide and water. However, most eukaryotes can generate some energy in the absence of oxygen by anaerobic metabolism.
Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...
Fermentation is a type of metabolic process that occurs in the absence of oxygen, where organic molecules such as glucose are broken down to produce energy. During this process, the...
129.2K