Related Experiment Video
Updated: Jan 31, 2026

A Reproducible Cartilage Impact Model to Generate Post-Traumatic Osteoarthritis in the Rabbit
Published on: November 21, 2023
Effect of neurocentral cartilage destruction on spinal growth in immature rabbits
Jie Wen1,2, Dahui Wang1, Ke Fang2
11 Department of Orthopedics, The Children's Hospital of Fudan University, Shanghai, China.
Objective:
This study was performed to observe the effect of neurocentral cartilage (NCC) destruction on spinal growth in immature rabbits.
Methods:
The NCC of the lumbar vertebrae of 24 4-week-old female rabbits was destroyed through posterolateral and anterior approaches, and three-dimensional computed tomography examinations were performed 3 months after the procedure.
Results:
Scoliosis was successfully induced in all rabbits of both the anterior and posterolateral approach groups. The scoliosis exceeded 10 degrees in three rabbits, which exhibited coronal scoliosis of the spine, unequal length and thickness of the bilateral pedicles, and rotation of the vertebrae. Scoliosis was not observed in the control group.
Conclusions:
Destruction of the unilateral NCC in immature rabbits can induce structural scoliosis, similar to the pathological features of human scoliosis. The Cobb angles are similar after NCC destruction by a posterolateral approach and under direct vision via the anterior approach.
More Related Videos
14:19Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
08:41Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
Related Concept Videos
Growth of Cartilage and Bone Tissue
Non-destructive Tests for Concrete Strength
Population Growth
Meristems and Plant Growth
Spinal Cord
The Spinal Cord