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Related Concept Videos

Weak Base Solutions03:21

Weak Base Solutions

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Some compounds produce hydroxide ions when dissolved by chemically reacting with water molecules. In all cases, these compounds react only partially and so are classified as weak bases. These types of compounds are also abundant in nature and important commodities in various technologies. For example, global production of the weak base ammonia is typically well over 100 metric tons annually, being widely used as an agricultural fertilizer, a raw material for chemical synthesis of other...
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Weak Acid Solutions04:02

Weak Acid Solutions

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Few compounds act as strong acids. A far greater number of compounds behave as weak acids and only partially react with water, leaving a large majority of dissolved molecules in their original form and generating a relatively small amount of hydronium ions. Weak acids are commonly encountered in nature, being the substances partly responsible for the tangy taste of citrus fruits, the stinging sensation of insect bites, and the unpleasant smells associated with body odor. A familiar example of a...
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Titration of a Weak Acid with a Weak Base01:08

Titration of a Weak Acid with a Weak Base

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Weak acids and bases do not undergo dissociation completely, and titrations between these two are rarely studied. When such studies are performed, say, for the titration of a weak acid with a weak base, the titration curve plots the change in pH as a function of the volume of base added. Take the titration of acetic acid with ammonia, for instance. During the titration, these two species form ammonium acetate and water, but the pH change is slow and gradual.
As a result, there is no simple...
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State Space Representation01:27

State Space Representation

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The frequency-domain technique, commonly used in analyzing and designing feedback control systems, is effective for linear, time-invariant systems. However, it falls short when dealing with nonlinear, time-varying, and multiple-input multiple-output systems. The time-domain or state-space approach addresses these limitations by utilizing state variables to construct simultaneous, first-order differential equations, known as state equations, for an nth-order system.
Consider an RLC circuit, a...
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Titration Calculations: Weak Acid - Strong Base03:55

Titration Calculations: Weak Acid - Strong Base

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Calculating pH for Titration Solutions: Weak Acid/Strong Base
For the titration of 25.00 mL of 0.100 M CH3CO2H with 0.100 M NaOH, the reaction can be represented as:
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Control Volume and System Representations01:16

Control Volume and System Representations

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Two key frameworks are employed to analyze mass, energy, and momentum transfer: the control volume approach and the system approach. These frameworks offer different perspectives, depending on whether the focus is on a specific region in space (control volume approach) or a defined mass of fluid (system approach).
The control volume approach considers a stationary region in space through which fluid flows. This region is bounded by a control surface.  For instance, in the case of water...
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Related Experiment Video

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Author Spotlight: Insights into Remotely Supervised Neuromodulation Procedure for Phantom Limb Pain
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A clinical text classification paradigm using weak supervision and deep representation.

Yanshan Wang1, Sunghwan Sohn2, Sijia Liu2

  • 1Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, 200 1st ST SW, Rochester, MN, 55905, USA. wang.yanshan@mayo.edu.

BMC Medical Informatics and Decision Making
|January 9, 2019
PubMed
Summary
This summary is machine-generated.

This study introduces a new method for clinical text classification using weak supervision and deep representation, significantly reducing the need for manual data labeling and feature engineering. The approach, particularly with Convolutional Neural Networks (CNNs), shows strong performance in classifying smoking status and hip fractures.

Keywords:
Clinical text classificationElectronic health recordsMachine learningNatural language processingWeak supervision

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Area of Science:

  • Natural Language Processing (NLP)
  • Machine Learning in Healthcare
  • Clinical Informatics

Background:

  • Automatic clinical text classification leverages NLP to extract information from clinical narratives.
  • Machine learning models are effective but typically require extensive manual data labeling and feature engineering.
  • This study addresses the challenge of reducing human effort in clinical text classification.

Purpose of the Study:

  • To propose a novel clinical text classification paradigm using weak supervision and deep representation.
  • To reduce the human effort associated with creating labeled training data and conducting feature engineering.
  • To evaluate the effectiveness of this paradigm across multiple clinical text classification tasks.

Main Methods:

  • Developed a rule-based NLP algorithm for automatic training data labeling (weak supervision).
  • Utilized pre-trained word embeddings as deep representation features.
  • Evaluated four machine learning models (SVM, RF, MLPNN, CNN) on smoking status and hip fracture classification tasks.

Main Results:

  • Convolutional Neural Networks (CNNs) achieved the highest performance (F1 scores of 0.92 for smoking status and 0.97 for hip fracture).
  • Word embeddings outperformed traditional features like tf-idf and topic modeling.
  • CNNs captured additional patterns beyond rule-based NLP, though they showed sensitivity to training data size and limitations in complex multiclass tasks.

Conclusions:

  • The proposed weak supervision and deep representation paradigm effectively reduces human effort in clinical text classification.
  • The approach is validated by strong performance on institutional and public datasets.
  • This method offers a more efficient pathway for applying machine learning to clinical text data.