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Updated: Jan 31, 2026

Three-dimensional Rendering and Analysis of Immunolabeled, Clarified Human Placental Villous Vascular Networks
Published on: March 29, 2018
Characterization of Placental Microvasculature Using Superb Microvascular Imaging
Lauren M Mack1, Joan M Mastrobattista1, Rajshi Gandhi1
1Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas, USA.
Abstract:
Superb Microvascular Imaging (SMI; Canon Medical Systems, Tustin, CA) uses clutter suppression to extract flow signals at rapid frame rates, which provides high-resolution vessel-branching details without the need for contrast agents. The potential diagnostic benefits of SMI, as described in other areas of medicine, requires further exploration during pregnancy. In this pictorial essay, we demonstrate the complementary use of SMI compared to conventional Doppler ultrasound and how it may improve our ability to characterize placental microvascular patterns without the need for ultrasound contrast agents.
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