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A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
Pulmonary artery interventions after the arterial switch operation: Unique and significant risks.
Jesse Lee1, Doaa Abdullah Shahbah1, Howaida El-Said1
1Department of Pediatric Cardiology, Rady Children's Hospital, University of California San Diego, San Diego, California.
Percutaneous intervention for pulmonary artery stenosis after arterial switch operation (ASO) carries high risks, including aorto-pulmonary fistula and coronary compression. Careful patient selection and consideration of reinforced covered stents are advised.
Area of Science:
- Cardiology
- Pediatric Cardiac Surgery
- Interventional Cardiology
Background:
- Arterial switch operation (ASO) for transposition of the great arteries yields excellent outcomes.
- The LeCompte maneuver during ASO may lead to pulmonary artery stenosis.
- Atypical complications like aorto-pulmonary fistula and coronary compression can occur after pulmonary artery stenting post-ASO.
Purpose of the Study:
- To review adverse events associated with pulmonary artery interventions in patients post-ASO.
- To evaluate the risks and outcomes of pulmonary artery stenting in this patient population.
Main Methods:
- Retrospective review of catheterizations in patients who underwent ASO.
- Analysis of 47 patients over a 10-year period, focusing on diagnostic and interventional procedures.
- Detailed examination of adverse events, particularly in patients undergoing pulmonary artery angioplasty and stenting.
Main Results:
- Five major adverse events (14%) occurred in 29 patients undergoing 37 interventions, including aorto-pulmonary fistulae and coronary artery compression.
- Six procedures (16%) were aborted due to high risk of adverse events.
- Stent implantation or redilation was associated with significant complications.
Conclusions:
- Percutaneous intervention for post-ASO pulmonary artery stenosis is high-risk and requires cautious application.
- Thorough pre-procedural evaluation of coronary arteries is essential due to potential proximity to stenosis.
- Risks of stent fracture and aorto-pulmonary fistula necessitate consideration of reinforced covered stents.
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