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Updated: Jan 31, 2026

Transradial Access Chemoembolization for Hepatocellular Carcinoma Patients
Published on: September 20, 2020
Critical systematic review on hepatic resection and transarterial chemoembolization for hepatocellular carcinoma
Leonardo Solaini1,2, Alessandro Cucchetti1,2, Marco Piccino3
1General and Oncology Surgery, Morgagni-Pierantoni Hospital, Forli, 47121, Italy.
Abstract:
Whether to submit to transarterial chemoembolization (TACE) or hepatic resection (HR) patients with hepatocellular carcinoma (HCC) is still a debated issue. We conducted a systematic review to critically analyze what evidence supports the use of TACE, in a specific clinical condition that can define HCC as 'intermediate'. In addition, we analyzed literature regarding the comparison between TACE and HR. Direct comparisons, between HR and TACE, strongly support the adoption of surgery for patients with large or multinodular HCCs since, albeit 'nonideal' surgical candidates, these patients can still obtain a survival benefit. Multidisciplinary teams can mitigate the different decision-making approach of surgeons and hepatologists with the aim of obtaining the best quality of care.
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