Related Experiment Video
Updated: Jan 31, 2026
Therapeutic Effectiveness of a Dietary Supplement for Management of Halitosis in Dogs
Published on: July 6, 2015
Short- and Long-Term Effects of a Dentifrice Containing Dual Zinc plus Arginine on Intra-Oral Halitosis: Improvements
Saliha Saad1, Michael Fitzgerald2, Keith Hewett1
1University of the West of England Faculty of Health and Applied Science, Bristol, UK.
Objectives:
These studies aimed to assess the short-term (12-hour, single use) and long-term (four weeks, continuous use) efficacy of a new Dual Zinc plus Arginine dentifrice against intra-oral halitosis versus a negative control.
Methods:
Two clinical studies were conducted to assess the dentifrice: a four-week, continuous use parallel design versus a negative control and a single use crossover design versus a negative control. Both studies used organoleptic and hedonic odor judge scores measured 12 hours overnight after product use as the primary efficacy variable. Additionally, the single use study employed SIFT-MS to quantify the intra-oral concentration of volatile sulfur compounds as a complementary measure of efficacy.
Results:
In both studies, the Dual Zinc plus Arginine dentifrice provided statistically significant improvements in breath quality across all measures versus a negative control.
Conclusions:
Improvements in breath quality were attributed to the effects of zinc cations delivered by the uniquely formulated dentifrice.
Related Concept Videos
01:05Breathing
01:05Long-term Depression
01:11Oral Cavity
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
01:30Mechanism of Breathing I: Inspiration
The respiratory system, an essential network for breathing, comprises the conducting and respiratory zones, each playing a crucial role in the overall process of respiration. Let us explore the detailed mechanism of inspiration, or inhalation, which is the first phase of the respiratory cycle.
Pathway of Air during Inspiration
During inspiration, air enters our body through the nose or mouth and moves through the conducting zone,...
01:23Mechanism of Breathing II: Expiration
Expiration, or exhaling, is a complex physiological process that begins as the inspiratory muscles begin to relax. This relaxation triggers a series of events that epitomize the efficiency of the respiratory system.
Mechanism of Expiration:
03:26Framing Effects