Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Introduction to Epidemiology01:26

Introduction to Epidemiology

1.8K
Epidemiology, known as the cornerstone of public health, involves studying the distribution and determinants of health-related events in defined populations and applying these insights to control health issues. This is essential for understanding how diseases spread, identifying populations at greater risk, and implementing measures to control or prevent outbreaks. Epidemiology addresses not only infectious diseases but also non-communicable conditions like cancer and cardiovascular disease,...
1.8K
Causality in Epidemiology01:21

Causality in Epidemiology

1.6K
Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
1.6K
Definite Integral01:29

Definite Integral

66
Consider a real-valued function defined on a closed interval. One of the fundamental objectives in calculus is to determine the area under the graph of such a function. When an exact computation is not readily available, this area can be estimated by dividing the interval into a finite number of equal subintervals. Each subinterval corresponds to a rectangle whose width is the length of the subinterval and whose height is determined by the value of the function at a selected point within that...
66
Definition of z-Transform01:26

Definition of z-Transform

1.6K
The z-transform is a powerful mathematical tool used in the analysis of discrete-time signals and systems. It is an essential analytical tool, analogous to the Laplace transform used in continuous-time systems. It plays a crucial role in the analysis of signals and systems, complementing the discrete-time Fourier transform. Both the z-transform and the Laplace transform convert differential or difference equations into algebraic equations, simplifying the process of solving complex problems.
1.6K
Study Designs in Epidemiology01:20

Study Designs in Epidemiology

967
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
967
Confounding in Epidemiological Studies01:27

Confounding in Epidemiological Studies

802
Confounding in statistical epidemiology represents a pivotal challenge, referring to the distortion in the perceived relationship between an exposure and an outcome due to the presence of a third variable, known as a confounder. This variable is associated with both the exposure and the outcome but is not a direct link in their causal chain. Its presence can lead to erroneous interpretations of the exposure's effect, either exaggerating or underestimating the true association. This...
802

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of a clinical metagenomics intervention on clinical outcomes, healthcare costs, and health-related quality of life in patients with sepsis or septic shock: results of the randomized-controlled DigiSep trial.

Intensive care medicine·2026
Same author

The Cellular Response Capacity as Diagnostic Head Start in Neutrophil Endotoxemia Sensing.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026
Same author

Impact of cardiopulmonary bypass on cefuroxime plasma and interstitial tissue concentrations in patients undergoing cardiac bypass surgery-a prospective controlled clinical trial.

The Journal of antimicrobial chemotherapy·2026
Same author

[High-flow oxygen in acute hypoxemic respiratory failure: no improved survival but clinically relevant? : Commentary on the SOHO trial].

Medizinische Klinik, Intensivmedizin und Notfallmedizin·2026
Same author

The cellular response capacity (CRC) as a novel immunomonitoring approach in sepsis.

Military Medical Research·2026
Same author

The time has come for optimizing beta-lactam therapy in critically ill patients with renal dysfunction.

Intensive care medicine·2026

Related Experiment Video

Updated: Jan 31, 2026

Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis
04:01

Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis

Published on: June 14, 2024

1.5K

[Sepsis Update: Definition and Epidemiology].

Hendrik Bracht, Sebastian Hafner, Manfred Weiß

    Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS
    |January 9, 2019
    PubMed
    Summary

    Sepsis, a critical illness in intensive care units, lacks specific treatments. Early diagnosis of sepsis is vital for improving patient outcomes through prompt infection control and hemodynamic stabilization.

    Area of Science:

    • Critical Care Medicine
    • Infectious Diseases
    • Epidemiology

    Background:

    • Sepsis is a prevalent and life-threatening condition in intensive care units globally.
    • Despite extensive research, a specific curative therapy for sepsis remains elusive.
    • Early intervention is crucial for improving sepsis patient outcomes.

    Purpose of the Study:

    • To review and compare historical and current definitions of sepsis.
    • To provide an epidemiological overview of sepsis.
    • To emphasize the importance of accurate sepsis definition for diagnosis and management.

    Main Methods:

    • Literature review of sepsis definitions.
    • Analysis of epidemiological data on sepsis incidence and prevalence.
    • Synthesis of information on diagnostic criteria and clinical presentation.

    More Related Videos

    Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies
    07:34

    Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies

    Published on: April 11, 2012

    20.1K
    A Data-Driven Approach to Quantifying Immune States in Sepsis
    07:42

    A Data-Driven Approach to Quantifying Immune States in Sepsis

    Published on: February 7, 2025

    540

    Related Experiment Videos

    Last Updated: Jan 31, 2026

    Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis
    04:01

    Author Spotlight: Advanced Integrated Model for Sepsis-Induced Myopathy and Single-Cell Metabolic Analysis

    Published on: June 14, 2024

    1.5K
    Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies
    07:34

    Use of Animal Model of Sepsis to Evaluate Novel Herbal Therapies

    Published on: April 11, 2012

    20.1K
    A Data-Driven Approach to Quantifying Immune States in Sepsis
    07:42

    A Data-Driven Approach to Quantifying Immune States in Sepsis

    Published on: February 7, 2025

    540

    Main Results:

    • Sepsis definitions have evolved over time, impacting diagnostic accuracy.
    • Epidemiological data highlight the significant burden of sepsis worldwide.
    • No specific therapy exists, underscoring the importance of early diagnosis and management.

    Conclusions:

    • Accurate and sensitive sepsis definitions are indispensable for timely diagnosis.
    • Effective sepsis management relies on early infection source control, appropriate antibiotics, and hemodynamic support.
    • Continued research into sepsis pathogenesis and treatment is warranted.