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Related Experiment Video

Updated: Jan 31, 2026

A Protocol for Rapid Post-mortem Cell Culture of Diffuse Intrinsic Pontine Glioma DIPG

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Published on: March 7, 2017

Predictive equation to estimate post-mortem interval using spectrophotometric blood-colour values.

Yosuke Usumoto^1,2, Keiko Kudo², Akiko Tsuji²

¹1 Department of Legal Medicine, Yokohama City University Graduate School of Medicine, Japan.

Medicine, Science, and the Law

|January 10, 2019

Summary

This study explores using blood color to estimate the post-mortem interval (PMI). Spectrophotometric analysis of blood samples from 129 cadavers provided accurate PMI estimations up to 67 hours.

Keywords:

Post-mortem lividity blood colour post-mortem interval (PMI)spectrophotometer

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Area of Science:

Forensic science
Biophysics
Analytical chemistry

Background:

Forensic pathologists utilize post-mortem phenomena to determine the time since death.
Previous research highlighted the utility of post-mortem lividity spectrophotometry for post-mortem interval (PMI) estimation.
This study investigates the potential of blood color as a novel indicator for PMI estimation.

Purpose of the Study:

To explore the association between blood color, age, and PMI.
To develop predictive equations for estimating PMI based on blood color spectrophotometric values.
To assess the accuracy of PMI estimations derived from blood color analysis.

Main Methods:

Spectrophotometric analysis of blood samples from 129 cadavers (84 males, 45 females).
Measurement of left ventricular, right ventricular, and femoral blood color parameters (L*, a*, b*).
Development and validation of predictive equations for blood color and PMI estimation.

Main Results:

No significant association found between overall blood color and age or PMI.
Specific blood color parameters (a*l, b*l, a*r, b*r) increased with age.
Femoral blood color equations demonstrated higher accuracy (higher R², lower RMSE) than ventricular equations.
PMI estimations up to 67 hours showed accuracy within 8.84 hours, independent of lividity color or age.

Conclusions:

Blood color spectrophotometry offers a novel method for estimating post-mortem intervals.
Femoral blood color analysis provides more reliable PMI estimations compared to ventricular blood.
This technique offers accurate PMI estimations without the need for post-mortem lividity measurements or age consideration.