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Multicentre pilot study evaluation of lung ultrasound for the management of paediatric pneumonia in low-resource

Jennifer L Lenahan1, Giovanni Volpicelli2, Alessandro Lamorte3

  • 1International Programs, Save the Children Federation Inc, Fairfield, Connecticut, USA.

BMJ Open Respiratory Research
|January 10, 2019
PubMed

Insights

Lung ultrasound (LUS) shows promise for diagnosing childhood pneumonia in low-resource settings. This pilot study in Mozambique and Pakistan evaluated LUS feasibility and effectiveness in diagnosing pediatric pneumonia.

Area of Science:

  • Pediatric infectious diseases
  • Medical imaging
  • Global health

Background:

  • Pneumonia is a leading cause of death in children under five globally.
  • Accurate diagnosis of pneumonia remains a challenge, particularly in resource-limited areas.
  • Lung ultrasound (LUS) is an emerging technology with potential for diagnosing childhood pneumonia.

Purpose of the Study:

  • To pilot lung ultrasound (LUS) in Mozambique and Pakistan.
  • To generate evidence on the utility of LUS for diagnosing childhood pneumonia in low-resource settings.
  • To assess the feasibility, usability, and acceptability of LUS among healthcare providers and caregivers.

Main Methods:

  • A pilot study enrolled 270 children with cough in Mozambique and Pakistan.
  • Standard clinical assessments, chest radiography, and LUS examinations were performed.
  • Specimens were collected for pathogen and biomarker analysis, with follow-up for 30 days.

Main Results:

  • The primary outcome is LUS findings at enrollment.
  • Secondary outcomes include patient outcomes, repeat LUS findings, and diagnostic test results.
  • Data on feasibility, usability, and acceptability of LUS were also collected.

Conclusions:

  • Lung ultrasound (LUS) is a promising tool for diagnosing childhood pneumonia.
  • Further research is needed to understand the role of LUS in low-resource settings.
  • This study provides initial evidence on the feasibility and potential of LUS in these contexts.
Abstract

Keywords:
imaging/CT MRI etcpaediatric lung disaesepneumoniarespiratory infection

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