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Rous Sarcoma Virus (RSV) and Cancer01:03

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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An Improved and High Throughput Respiratory Syncytial Virus RSV Micro-neutralization Assay
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Is it RSV?

Christopher S Ambrose1

  • 1AstraZeneca Pharmaceuticals One MedImmune Way Gaithersburg Maryland USA.

Health Science Reports
|January 10, 2019
PubMed
Summary
This summary is machine-generated.

Respiratory syncytial virus (RSV) causes infant bronchiolitis. Episodes during winter, in younger infants, and with higher care levels were more likely RSV-related.

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Area of Science:

  • Pediatrics
  • Virology
  • Epidemiology

Background:

  • Infant bronchiolitis is a common respiratory infection.
  • Respiratory syncytial virus (RSV) is a primary causative agent.
  • Understanding RSV attribution is crucial for public health.

Purpose of the Study:

  • To determine the proportion of infant bronchiolitis episodes attributable to RSV.
  • To identify factors associated with RSV-positive bronchiolitis.

Main Methods:

  • Analysis of infant bronchiolitis-coded episodes.
  • Statistical evaluation of contributing factors.

Main Results:

  • RSV was a significant contributor to infant bronchiolitis episodes.
  • Episodes during peak winter viral season showed higher RSV attribution.
  • Younger infants and those requiring higher levels of care had increased RSV likelihood.

Conclusions:

  • RSV is a major driver of infant bronchiolitis, particularly during winter.
  • Infant age and healthcare utilization are key indicators for RSV risk.
  • Findings inform targeted prevention and management strategies for RSV bronchiolitis.