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Myocardial revascularization in women.
The Annals of Thoracic Surgery
|May 1, 1978
Summary
Coronary artery bypass grafting outcomes improved for women, with declining mortality rates and similar five-year survival to men. These findings suggest myocardial revascularization is a viable option for female patients.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Outcomes
- Gender Differences in Medicine
Background:
- Historically, higher operative mortality rates for women undergoing coronary artery bypass grafting (CABG) have been reported.
- Understanding contemporary outcomes in female CABG patients is crucial for equitable treatment.
Purpose of the Study:
- To evaluate operative mortality, graft patency, and long-term survival in women undergoing CABG compared to men.
- To assess trends in outcomes for women over time.
Main Methods:
- Retrospective analysis of 1,541 patients undergoing CABG between 1970 and 1977.
- Comparison of outcomes between men and women, including operative mortality, graft patency, and survival rates.
Main Results:
- Operative mortality in women declined significantly from 3.7% to 1.4% in later years (1975-1977).
- Women had more severe angina and better preoperative ventricular function but lower graft patency rates.
- Five-year survival rates were comparable between genders (88.3% in women vs. 93.5% in men).
Conclusions:
- Contemporary CABG outcomes for women have improved, with mortality rates approaching those of men.
- Lower graft patency in women may relate to smaller coronary artery size.
- Myocardial revascularization should not be withheld from female patients due to perceived higher risk.