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The Relationship between Heart Rate Variability and Aortic Knob Width

Si-Yeun Sung1, Jee-Hye Han1, Jung-Hwan Kim1

  • 1Department of Family Medicine, Nowon Eulji Medical Center, Eulji University, Seoul, Korea.

Korean Journal of Family Medicine
|January 10, 2019
PubMed

Insights

Aortic knob width (AKW) is linked to heart rate variability (HRV) parameters, indicating potential cardiovascular disease risk. Lower HRV values were observed with wider AKW, suggesting a significant association.

Area of Science:

  • Cardiology
  • Radiology
  • Physiology

Background:

  • Aortic knob width (AKW) and heart rate variability (HRV) are potential indicators of cardiovascular disease.
  • The direct relationship between AKW and HRV has not been previously explored.

Purpose of the Study:

  • To investigate the association between aortic knob width and heart rate variability parameters in a Korean population.
  • To determine if AKW is a predictor of altered heart rate variability.

Main Methods:

  • 587 Korean adults (18-79 years) underwent physical measurements, medical history review, blood tests, and chest radiography.
  • Heart rate variability (HRV) was assessed using parameters like SDNN, RMSSD, ApEn, TP, VLF, LF, HF, and LF/HF ratio over 5 minutes.
  • Aortic knob width (AKW) was measured from chest radiographs by a single reviewer.

Main Results:

  • A significant correlation was found between AKW and most HRV parameters (SDNN, RMSSD, ApEn, TP, VLF, LF, HF), excluding the LF/HF ratio.
  • HRV parameter values decreased as AKW quartile groups increased.
  • After adjusting for various clinical and lifestyle factors, AKW maintained significant negative associations with HRV parameters (except LF/HF ratio).

Conclusions:

  • Aortic knob width is significantly associated with key heart rate variability parameters, including SDNN, RMSSD, ApEn, TP, VLF, LF, and HF.
  • These findings suggest a potential link between aortic morphology and autonomic nervous system function.
Abstract

Keywords:
Aortic Knob WidthCardiovascular DiseasesHeart Rate VariabilityThoracic Aorta

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