Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Fluid Mosaic Model

The Fluid Mosaic Model

The fluid mosaic model was first proposed as a visual representation of research observations. The model comprises the composition and dynamics of membranes and serves as a foundation for future membrane-related studies. The model depicts the structure of the plasma membrane with a variety of components, which include phospholipids, proteins, and carbohydrates. These integral molecules are loosely bound, defining the cell’s border and providing fluidity for optimal function.

Gene Therapy

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...

Constant Volume Calorimetry

Constant Volume Calorimetry

Calorimeters are useful to determine the heat released or absorbed by a chemical reaction. Coffee cup calorimeters are designed to operate at constant (atmospheric) pressure and are convenient to measure heat flow (or enthalpy change) accompanying processes that occur in solution at constant pressure. A different type of calorimeter that operates at constant volume, colloquially known as a bomb calorimeter, is used to measure the energy produced by reactions that yield large amounts of heat and...

Volume of Distribution

Volume of Distribution

The apparent volume of distribution (Vd) is a crucial pharmacokinetic parameter representing the hypothetical body fluid volume into which a drug disperses. It is calculated based on the total amount of drug in the body (estimated from the administered dose and bioavailability) divided by the plasma drug concentration. The total amount of drug in the body does not directly refer to the dose given but is derived by accounting for absorption, distribution, metabolism, and excretion processes.

Problem Solving: Volume

Problem Solving: Volume

The volume of a fuel tank mounted on the wing of a jet aircraft can be modeled using the concept of solids of revolution. In this case, the tank is formed by rotating a two-dimensional region, defined by a mathematical function, about the x-axis. The region extends along the axis from zero to two meters, and the resulting three-dimensional shape is symmetric about the axis of rotation. Because the boundary curve lies directly against the axis, the disk method is an appropriate technique for...

Respiratory Volumes

Respiratory Volumes

Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Spinal Versus General Anesthesia for Acute Kidney Injury and Transfusion in One-Week-Staged Bilateral Total Knee Arthroplasty.

Journal of clinical medicine·2026

Same author

Second-knee transfusion burden persists under a high-dose intravenous iron protocol without tranexamic acid in one-week staged bilateral total knee arthroplasty: a paired cohort study.

BMC musculoskeletal disorders·2026

Same author

Scapular dyskinesis with preserved structure and function in largely asymptomatic junior elite tennis players: a 2D video and multimodal cross-sectional study.

BMC sports science, medicine & rehabilitation·2026

Same author

Diversification of angiosperm reproductive strategies predated the end-Cretaceous extinction.

Science (New York, N.Y.)·2026

Same author

A novel Tie2xVEGF bispecific antibody fusion demonstrates enhanced therapeutic efficacy through direct Tie2 activation and VEGF neutralization.

Journal of translational medicine·2026

Same author

Invasive plants reduce functional feeding diversity and trophic interactions of insect herbivores on a remote tropical island.

PloS one·2026

Search research articles

Related Experiment Video

Updated: Jan 31, 2026

Intraoperative Ultrasound in Spinal Surgery

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

Plasma volume expanders and intraoperative fluid therapy.

¹Department of Anesthesiology and Pain Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. jmlee@catholic.ac.kr.

Korean Journal of Anesthesiology

|January 11, 2019

Summary

Intraoperative fluid therapy for surgical patients involves choosing between colloid and crystalloid solutions, debating different colloid types, and deciding on high or low volume strategies. This overview aims to clarify these complex issues in fluid management.

Keywords:

Colloid Crystalloid Fluid therapy Intraoperative Volume replacement

More Related Videos

Basic Research in Plasma Medicine - A Throughput Approach from Liquids to Cells

Basic Research in Plasma Medicine - A Throughput Approach from Liquids to Cells

Published on: November 17, 2017

Real-time X-ray Imaging of Lung Fluid Volumes in Neonatal Mouse Lung

Real-time X-ray Imaging of Lung Fluid Volumes in Neonatal Mouse Lung

Published on: July 18, 2016

Related Experiment Videos

Last Updated: Jan 31, 2026

Intraoperative Ultrasound in Spinal Surgery

Intraoperative Ultrasound in Spinal Surgery

Published on: August 17, 2022

Basic Research in Plasma Medicine - A Throughput Approach from Liquids to Cells

Basic Research in Plasma Medicine - A Throughput Approach from Liquids to Cells

Published on: November 17, 2017

Real-time X-ray Imaging of Lung Fluid Volumes in Neonatal Mouse Lung

Real-time X-ray Imaging of Lung Fluid Volumes in Neonatal Mouse Lung

Published on: July 18, 2016

Area of Science:

Anesthesiology
Surgical Patient Management
Fluid Therapy

Background:

Adequate intravascular volume restoration is critical for surgical patients.
Current fluid replacement strategies lack clear guidelines, often relying on tradition.
Debates persist regarding optimal fluid choices and volumes.

Purpose of the Study:

To review and present different fluid solutions for intraoperative therapy.
To address the ongoing controversies in fluid management for surgical patients.
To facilitate evidence-based strategies for volume replacement.

Main Methods:

Literature review and synthesis of current evidence.
Analysis of the colloid versus crystalloid debate.
Examination of colloid versus colloid choices.
Discussion of high versus low volume replacement strategies.

Main Results:

The choice between colloids and crystalloids remains controversial.
An expanding array of colloid solutions fuels further debate.
The optimal volume replacement strategy (high vs. low) is debated among anesthesiologists.

Conclusions:

Intraoperative fluid therapy requires careful consideration of multiple controversial factors.
Evidence-based strategies are needed to move beyond traditional approaches.
This overview provides a framework for optimizing fluid management in surgical patients.