Distribution of Bacillus Calmette-Guérin (BCG) Vaccine in Victoria 2013-2015

Nicole X Wong1,2, Nigel Crawford3,4,2, Jock Lawrie5

  • 1Monash Children's Hospital, Melbourne. General Medicine, Royal Children's Hospital (RCH), Melbourne.

Insights

The Bacillus Calmette-Guérin (BCG) vaccine is crucial for preventing tuberculosis (TB) in high-risk children. Analysis revealed disparities in BCG vaccine distribution, particularly for infants of African background, indicating a need for improved awareness and equitable access.

Area of Science:

  • Immunology
  • Vaccinology
  • Public Health

Background:

  • The Bacillus Calmette-Guérin (BCG) vaccine plays a vital role in mitigating tuberculosis (TB) disease among high-risk children.
  • In Victoria, the Royal Children's Hospital (RCH) and Monash Health (MH) have been the primary providers of the BCG vaccine since 2013.

Purpose of the Study:

  • To conduct a retrospective analysis of BCG vaccine distribution at RCH and MH.
  • To compare BCG vaccine uptake across various demographic cohorts with local birth data.
  • To identify potential inequities in BCG vaccine service delivery.

Main Methods:

  • Retrospective analysis of patients receiving BCG vaccine at RCH and MH between November 1, 2013, and November 30, 2015.
  • Comparison of patient data with Victorian birth data from 2012.
  • Analysis of demographic factors including parental ethnicity and travel destinations.

Main Results:

  • A total of 3,975 patients received the BCG vaccine; detailed data was available for 830 RCH patients.
  • The majority of vaccinations (98.9%) were for children traveling to Asia.
  • A significant disparity was observed in the uptake of the BCG vaccine among infants of African background compared to Victorian birth data, suggesting a need for improved awareness and equity.

Conclusions:

  • The study highlights potential gaps in awareness and equity of BCG vaccine services.
  • There is a particular need to improve access for infants of African background.
  • Optimizing BCG vaccine delivery can enhance protection against TB in vulnerable populations.
Abstract