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Plaquing of Herpes Simplex Viruses
Published on: November 5, 2021
An Adult Case of Herpes Simplex Virus-associated Granulomatous Encephalitis
Yuta Iwai1, Kazutaka Nishimura1, Takeshi Fukushima1
1Department of Neurology, Matsudo City General Hospital, Japan.
Abstract:
Brain granuloma occurs under certain conditions. Herpes simplex virus (HSV) causes granulomatous encephalitis in children; however, it has been rarely reported in adults. A 74-year-old man with a history of herpes simplex encephalitis suffered recurrent seizures. Brain magnetic resonance imaging revealed a mass lesion and resection was performed. A polymerase chain reaction using a brain biopsy specimen was positive for HSV DNA; thus, the patient was diagnosed with HSV-associated granulomatous encephalitis. After administering acyclovir, the patient showed improvement. HSV can cause granulomatous encephalitis in adults, and acyclovir can be used for its treatment.
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