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Related Experiment Video

Updated: Jan 31, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Defining Cognitive Reserve and Implications for Cognitive Aging.

Corinne Pettigrew¹, Anja Soldan²

¹Department of Neurology, Johns Hopkins University School of Medicine, 1620 McElderry St., Reed Hall 1-West, Baltimore, MD, 21205, USA.

Current Neurology and Neuroscience Reports

|January 11, 2019

Summary

This summary is machine-generated.

Cognitive reserve (CR) may protect against cognitive decline in aging and Alzheimer's disease. Higher CR is linked to better performance and reduced dementia risk, but more research is needed on its mechanisms.

Keywords:

Aging Alzheimer’s disease Biomarkers Cognition Cognitive reserve Review

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Published on: January 24, 2020

Area of Science:

Neuroscience
Gerontology
Cognitive Psychology

Background:

Cognitive reserve (CR) is a key concept in understanding brain resilience.
CR is thought to mitigate the clinical impact of neuropathology in aging and neurodegenerative diseases like Alzheimer's.

Purpose of the Study:

To review current conceptual models of cognitive reserve.
To examine the evidence for CR in the context of aging and Alzheimer's disease.

Main Methods:

Literature review of conceptual models and empirical evidence.
Synthesis of findings related to proxy measures of CR and their impact on cognition.

Main Results:

Higher CR, indicated by lifetime experiences, correlates with better cognitive performance.
CR is associated with a reduced risk of mild cognitive impairment and dementia.
The impact of CR on long-term cognitive changes and its influence on brain structure require further investigation.

Conclusions:

Cognitive reserve offers a potential mechanism for maintaining cognitive function and well-being during aging.
CR can be enhanced throughout life, suggesting a modifiable target for interventions.
Further research is essential to elucidate the precise mechanisms underlying the protective effects of CR.