Related Experiment Video
Updated: Jan 31, 2026
06:12
Author Spotlight: A Novel Method for Comprehensive Cell Component Analysis of Cerebral Blood Clots
Published on: July 21, 2023
1.1K
Adults with Down syndrome: a comprehensive approach to manage complexity
A Carfì1, D L Vetrano1, D Mascia1
1Centro Medicina dell'Invecchiamento, Department of Geriatrics, Università Cattolica del Sacro Cuore, Rome, Italy.
Journal of Intellectual Disability Research : JIDR
|January 11, 2019
Summary
Adults with Down syndrome (DS) show high complexity and frequent geriatric conditions. Comprehensive assessment and management are needed for adequate care in this population.
Area of Science:
- Geriatric Medicine
- Intellectual Disability Research
- Down Syndrome Studies
Background:
- Down syndrome (DS) is associated with premature aging and comorbidities similar to the elderly.
- Limited data exists on the specific characteristics of adults with DS.
- This study addresses the knowledge gap regarding adult DS characteristics.
Purpose of the Study:
- To describe the characteristics of adults with Down syndrome.
- To utilize a standardized, comprehensive assessment instrument for data collection.
- To provide insights into the health and social profiles of adults with DS.
Main Methods:
- Cross-sectional study involving 430 adults with DS (aged 18-75).
- Participants recruited from Italy, USA, and Canada.
- Data collected using the interRAI intellectual disability standardized assessment instrument.
Main Results:
- Mean age varied across samples, with Canadian adults being older on average.
- Residential settings differed, with more Canadian participants institutionalized.
- High prevalence of geriatric conditions (cognitive deficits, ADL disability, behavioral issues, falls, hearing loss) and other issues (GI, skin, dental, obesity) observed.
Conclusions:
- Adults with Down syndrome exhibit significant complexity and require comprehensive care.
- A holistic assessment and management approach is suggested for effective care.
- Further research is necessary to evaluate the efficacy of such approaches in the DS population.
Related Concept Videos
01:26Acute Coronary Syndrome V: Nursing Management
325
Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
325
01:26Nephrotic Syndrome II : Assessment and Medical Management
239
IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...
239
01:24Nephrotic Syndrome III : Nursing Management
320
Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
320
01:30Irritable Bowel Syndrome III: Medical and Nursing Management
758
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
758
02:41Protein Complex Assembly
16.7K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types. Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
Many viruses self-assemble into a fully functional unit using the infected host cell to...
16.7K
01:57Protein Complexes with Interchangeable Parts
2.9K
Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
2.9K