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Stenosis of the Inferior Vena Cava: A Murine Model of Deep Vein Thrombosis
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Catheter Aspiration With Recanalization for Budd-Chiari Syndrome With Inferior Vena Cava Thrombosis

Fang Yang1, Ping-Chao Huang2, Lei-Lei Yan2

  • 1Department of Infectious and Liver Disease, Affiliated Hospital of Binzhou Medical College.

Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
|January 11, 2019
PubMed

Insights

Catheter aspiration with recanalization safely and effectively treats Budd-Chiari syndrome (BCS) and inferior vena cava (IVC) thrombosis. This minimally invasive procedure achieved high technical and clinical success rates with excellent long-term patency.

Area of Science:

  • Interventional Radiology
  • Vascular Medicine
  • Hepatology

Background:

  • Budd-Chiari syndrome (BCS) involves hepatic venous outflow obstruction.
  • Inferior vena cava (IVC) thrombosis is a common complication of BCS.
  • Effective treatment strategies for IVC thrombosis in BCS are crucial.

Purpose of the Study:

  • To evaluate the safety and clinical effectiveness of catheter aspiration with recanalization for IVC thrombosis in BCS patients.
  • To assess technical success, clinical success, and long-term patency rates.

Main Methods:

  • A cohort of 33 BCS patients with IVC thrombosis underwent catheter aspiration and IVC recanalization.
  • A 12F angled-tip guiding catheter was utilized for thrombus aspiration.
  • Recanalization techniques included balloon dilation and stent insertion.

Main Results:

  • The procedure demonstrated 100% technical and clinical success.
  • Complete thrombus resolution occurred in 21 patients; residual thrombi in 12.
  • Cumulative 1-, 3-, and 5-year IVC patency rates were 93.6%, 93.6%, and 83.2% respectively.
  • Low rates of pulmonary embolism were observed (1 symptomatic, 1 asymptomatic).

Conclusions:

  • Catheter aspiration with recanalization is a safe and effective treatment for BCS with IVC thrombosis.
  • The technique offers promising long-term patency and good clinical outcomes.
  • This minimally invasive approach is a valuable therapeutic option.
Abstract

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