[One year of infectious diseases in review]

New data were published regarding fœtal damage of Zika virus infection, and its sexual transmission. An outbreak of Ebola virus disease in the Democratic Republic of the Congo emphasizes the importance of vaccine development. In Switzerland, hospitals in the Canton of Bern were affected by a large outbreak of vancomycin-resistant enterococci. Despite the availability of new treatments, a significant decrease in the incidence of hepatitis C has not been achieved yet. Adjunctive rifampicin for Staphylococcus aureus bacteraemia provides no overall benefit over standard therapy. In selected patients with left side endocarditis, changing to oral treatment was non inferior to continued intravenous antibiotic treatment. Carbapenems remain the preferred treatment for extended-spectrum beta-lactamase (ESBL) producing bacteria bloodstream infection. Nitrofurantoin resulted in better clinical outcome than fosfomycin among women with uncomplicated cystitis.