[Cardiopulmonary stress test in variable frequency stimulation: a comparison of Activitrax and Nova-MR pacemakers in...

In seven patients with implanted intermedics NOVA MR pacemakers, we examined the cardiopulmonary effects of maximum bicycle ergometer exercise for three types of pacing in a randomized sequence: VVI or AAI at 70/min (SSI 70), rate adaptive temperature controlled with the implanted NOVA MR, and rate adaptive activity controlled by means of a Medtronic Activitrax pacemaker taped to the chest wall, which triggered the implanted Nova MR in the VVT or AAT mode via skin electrodes. The maximum exercise tolerance was 67 W with SSI 70, 71 W with Activitrax and 91 W with Nova MR. The maximum oxygen uptake was accordingly 17.6 ml/min/kg with SSI 70, 19.5 ml/min/kg with Activitrax, and 21.5 ml/min/kg with Nova MR. The highest heart rate reached was 81 beats/min with SSI 70,98 beats/min with Activitrax and 118 beats/min with Nova MR. The rate increase from rest to maximum exercise was 11 beats/min with SSI 70,29 beats/min with Activitrax and 47 beats/min with Nova MR. An increase in exercise tolerance and maximum heart rate could be achieved with both rate adaptive types of pacing, but significantly more clearly with the temperature controlled Nova MR than with the activity controlled Activitrax. However, using a different form of exercise, e.g. treadmill ergometry, the rate response of the Activitrax would presumably have been somewhat clearer.