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Updated: Jan 30, 2026

Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury
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Normothermic Cardiac Arrest and Cardiopulmonary Resuscitation: A Mouse Model of Ischemia-Reperfusion Injury

Published on: August 30, 2011

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Potential organ donors after Out-of-Hospital Cardiac Arrest during a ten-year period in Stockholm, Sweden

P Af Geijerstam1, S Forsberg1, A Claesson1

  • 1Karolinska Institutet, Department of Medicine, Solna, Sweden; Center for Resuscitation Science, Stockholm, Sweden.

Resuscitation
|January 11, 2019
PubMed

Insights

Implementing uncontrolled donation after circulatory death (uDCD) in Stockholm could significantly expand the organ donor pool. This approach, focusing on out-of-hospital cardiac arrest (OHCA) patients, offers a vital opportunity to increase organ availability.

Area of Science:

  • Transplantation Medicine
  • Cardiology
  • Public Health

Background:

  • Current organ donation in Sweden relies on brain death criteria.
  • Circulatory death is a more common cause of death.
  • Donation after circulatory death (DCD) from out-of-hospital cardiac arrest (OHCA) patients could expand the donor pool.

Purpose of the Study:

  • To assess the potential donor pool size and characteristics for uncontrolled donation after circulatory death (uDCD) in Stockholm.
  • To evaluate the feasibility of implementing uDCD programs in a major metropolitan area.

Main Methods:

  • Retrospective analysis of data from the Swedish Register for cardiopulmonary resuscitation (SRCR) from 2006-2015.
  • Application of five distinct uDCD selection criteria protocols to OHCA cases.
  • Evaluation of potential organ donor candidates based on established criteria.

Main Results:

  • Between 1.5% and 7.5% of 9,793 OHCA cases met uDCD criteria across different protocols.
  • Potential uDCD candidates had a median age between 48-57 years.
  • Males constituted 67-76% of potential uDCD candidates.

Conclusions:

  • Implementation of a uDCD program in Stockholm has the potential to substantially increase the number of organ donors.
  • The study highlights the significant potential of uDCD for organ donation, even without considering real-life limitations.
Abstract

Keywords:
Cardiac arrestCardiopulmonary resuscitationOrgan donationOrgan procurement systemsSudden

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