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Store-operated calcium entry in disease: Beyond STIM/Orai expression levels

Sven Kappel1, Anna Borgström1, Paulina Stokłosa1

  • 1Institute of Biochemistry and Molecular Medicine, National Center of Competence in Research NCCR TransCure, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.

Seminars in Cell & Developmental Biology
|January 11, 2019
PubMed
Summary

Store-operated calcium entry (SOCE) regulates cellular calcium signaling. This review details SOCE regulatory mechanisms and proteins involved in diseases like cancer and neurodegeneration.

Keywords:
CRAC channelsGlycosylationOrai regulatory proteinspH

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